Silicosis.

Details

• Personal Author:
  Balaan MR ; Banks DE
• Description:
  Silicon (7440213) induced pulmonary disease was discussed in this review. Occupations including sandblasting, mining or tunneling, milling, pottery, glassmaking, foundry work, quarry work, and abrasive work have been found to pose a high risk to workers for silicosis. Pathological changes in the lungs of patients with chronic silicosis have included fibrosis of the visceral pleura and hyalinized intrapulmonary nodules along with the presence of birefringent material in the periphery. Progressive massive fibrotic lesions have resulted from the coalescence of the silicotic nodules. Acute silicosis has been distinguished by the presence of proteinaceous material in the alveoli along with hypertrophic type- II pneumocytes and a minimal amount of fibrosis. Studies have suggested that the fibrogenic effect of silica (14808607) may be due to the release of inflammatory mediators by silica activated alveolar macrophages. The clinical presentation, diagnosis, and natural history of silicosis were described and discussed. [Description provided by NIOSH]
• Subjects:
  Occupational Exposure Occupational Health Respiratory Tract Diseases Risk Assessment Risk Factors Safety Silicon Compounds Silicon Dioxide
• Keywords:
  NIOSH-Cooperative-Agreement; Silicon-compounds; Silica-dusts; Silicate-miners; Pulmonary-system-disorders; Physiopathology; Occupational-exposure; Risk-factors
• ISBN:
  9780316755672
• Publisher:
  Little, Brown and Company, Boston, Massachusetts
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Book
• Place as Subject:
  District of Columbia ; Massachusetts ; OSHA Region 1 ; OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  OECSP - Office of Extramural Coordination and Special Projects ; DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  345-358
• NIOSHTIC Number:
  nn:00222083
• Citation:
  Environmental and occupational medicine, second edition. Rom WN, ed. Boston, MA: Little, Brown and Company, 1992 Jan; :345-358
• CAS Registry Number:
  Quartz (SiO2) (CAS RN 14808-60-7) ; Silicon (CAS RN 7440-21-3)
• Editor(s):
  Rom WN
• Federal Fiscal Year:
  1992
• Performing Organization:
  Center to Protect Workers' Rights
• Peer Reviewed:
  False
• Start Date:
  19900928
• Source Full Name:
  Environmental and occupational medicine, second edition
• End Date:
  19970515
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/243313/cdc_243313_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]