Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Enstone, Joanne E. ; Myles, Puja R. ; Openshaw, Peter J.M. ; Gadd, Elaine M. ; Lim, Wei Shen ; Semple, Malcolm G. ; Read, Robert C. ; Taylor, Bruce L. ; McMenamin, James ; Armstrong, Colin ; Bannister, Barbara ; Nicholson, Karl G. ; Nguyen-Van-Tam, Jonathan S.
• Description:
  To determine clinical characteristics of patients hospitalized in the United Kingdom with pandemic (H1N1) 2009, we studied 1,520 patients in 75 National Health Service hospitals. We characterized patients who acquired influenza nosocomially during the pandemic (H1N1) 2009 outbreak. Of 30 patients, 12 (80%) of 15 adults and 14 (93%) of 15 children had serious underlying illnesses. Only 12 (57%) of 21 patients who received antiviral therapy did so within 48 hours after symptom onset, but 53% needed escalated care or mechanical ventilation; 8 (27%) of 30 died. Despite national guidelines and standardized infection control procedures, nosocomial transmission remains a problem when influenza is prevalent. Health care workers should be routinely offered influenza vaccine, and vaccination should be prioritized for all patients at high risk. Staff should remain alert to the possibility of influenza in patients with complex clinical problems and be ready to institute antiviral therapy while awaiting diagnosis during influenza outbreaks.
• Subjects:
  Adolescent Adult Aged Anti-Bacterial Agents Antiviral Agents Child Child, Preschool Female Hospitalization Humans Infant Infection Control Influenza, Human Influenza A Virus, H1N1 Subtype Male Middle Aged Pandemics Treatment Outcome Vaccination Young Adult

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• Source:
  Emerg Infect Dis. 17(4):592-598.
• Document Type:
  Journal Article
• Funding:
  MC_G1001212/Medical Research Council/United Kingdom ; Chief Scientist Office/United Kingdom ; Department of Health/United Kingdom
• Place as Subject:
  United Kingdom
• Volume:
  17
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:8905e330ccdc9a309be3eee2327ac7680d93b0525795637babdb25f081e2b569
• Download URL:
  https://stacks.cdc.gov/view/cdc/24328/cdc_24328_DS1.pdf
• File Type:
  [PDF - 176.64 KB ]