Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010
Published Date:Apr 2011
Source:Emerg Infect Dis. 17(4):592-598.
Influenza A Virus
Influenza A Virus, H1N1 Subtype
Pandemic (H1N1) 2009
Funding:MC_G1001212/Medical Research Council/United Kingdom
Chief Scientist Office/United Kingdom
Department of Health/United Kingdom
Description:To determine clinical characteristics of patients hospitalized in the United Kingdom with pandemic (H1N1) 2009, we studied 1,520 patients in 75 National Health Service hospitals. We characterized patients who acquired influenza nosocomially during the pandemic (H1N1) 2009 outbreak. Of 30 patients, 12 (80%) of 15 adults and 14 (93%) of 15 children had serious underlying illnesses. Only 12 (57%) of 21 patients who received antiviral therapy did so within 48 hours after symptom onset, but 53% needed escalated care or mechanical ventilation; 8 (27%) of 30 died. Despite national guidelines and standardized infection control procedures, nosocomial transmission remains a problem when influenza is prevalent. Health care workers should be routinely offered influenza vaccine, and vaccination should be prioritized for all patients at high risk. Staff should remain alert to the possibility of influenza in patients with complex clinical problems and be ready to institute antiviral therapy while awaiting diagnosis during influenza outbreaks.
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