Strategies for the treatment of pneumoconiosis.

Details

• Personal Author:
  Banks DE ; Cheng YH ; Ma JK ; Weber SL
• Description:
  Following a brief review of the pathogenesis of silicosis, this report considered important aspects of therapies for pneumoconiosis which have been tried. There has been an aggressive search for therapeutic agents and procedures in China for silicosis and coal workers' pneumoconiosis. Various treatments for silicosis and coal workers' pneumoconiosis were discussed, including protection of the alveolar macrophage from silica (14808607) toxicity by using an aluminum-citrate complex of poly-2-vinylpyridine-N-oxide or poly-4-vinylpyridine-N-oxide (PVNO); control of the immune and inflammatory response through use of immunosuppressive and corticosteroid therapies; control of fibroproliferative activity through the use of tetrandrine or xinin; prevention of associated disease through the use of antimycobacterial therapy and pneumococcal vaccine; the removal of dust, macrophage and cytokines through whole lung lavage; lung transplantation; and monoclonal antibody therapy. [Description provided by NIOSH]
• Subjects:
  Coal Coal Mining Lung Lung Diseases Mining Occupational Health Respiratory System Respiratory Tract Diseases Safety
• Keywords:
  NIOSH-Publication; NIOSH-Cooperative-Agreement; Medical-treatment; Lung-disease; Respiratory-system-disorders; Lung-cells; Alveolar-cells; Coal-miners; Lung-fibrosis
• ISBN:
  9781560531296
• ISSN:
  0885-114X
• Publisher:
  Hanley and Belfus, Inc.
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  District of Columbia ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  205-232
• Volume:
  8
• Issue:
  1
• NIOSHTIC Number:
  nn:00213429
• Citation:
  Occup Med: State of the Art Rev 1993 Jan; 8(1):205-232
• CAS Registry Number:
  Quartz (SiO2) (CAS RN 14808-60-7)
• Editor(s):
  Banks DE
• Federal Fiscal Year:
  1993
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  Center to Protect Workers' Rights
• Peer Reviewed:
  True
• Start Date:
  19900928
• Source Full Name:
  Occupational Medicine: State of the Art Reviews. The Mining Industry
• End Date:
  19970515
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/243248/cdc_243248_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]