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Drug-Resistant Pandemic (H1N1) 2009, South Korea1
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  1. Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, South Korea
    Personal Author:
    Yi, Hwajung; Lee, Joo-Yeon; Hong, Eun-Hye; Kim, Mi-Seon; Kwon, Donghyok; Choi, Jang-Hoon; Choi, Woo-Young; Kim, Ki-Soon; Lee, Jong-Koo; Oh, Hee-Bok; Kang, Chun;
    Published:
    Dec 2010
    Source:
    Emerg Infect Dis. 16(12):1938-1942.
    Description:
    To identify oseltamivir resistance, we analyzed neuraminidase H275Y mutations in samples from 10 patients infected with pandemic (H1N1) 2009 virus in South Korea who had influenza that was refractory to antiviral treatment with this drug. A neuramini...
    File Type:
    Filetype[PDF - 432.27 KB]
  2. Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, Mexico
    Personal Author:
    Ramirez-Gonzalez, José Ernesto; Gonzalez-Duran, Elizabeth; Alcantara-Perez, Patricia; Wong-Arambula, Claudia; Olivera-Diaz, Hiram; Cortez-Ortiz, Iliana; Barrera-Badillo, Gisela; Nguyen, Ha; Gubareva, Larisa; Lopez-Martinez, Irma; Díaz-Quiñonez, Jose Alberto; Lezana-Fernández, Miguel Angel; Gatell-Ramírez, Hugo Lopez; Villalobos, Jose Angel Cordova; Hernández-Avila, Mauricio; Alpuche-Aranda, Celia;
    Published:
    Feb 2011
    Source:
    Emerg Infect Dis. 17(2):283-286.
    Description:
    During May 2009-April 2010, we analyzed 692 samples of pandemic (H1N1) 2009 virus from patients in Mexico. We detected the H275Y substitution of the neuraminidase gene in a specimen from an infant with pandemic (H1N1) 2009 who was treated with oselta...
    File Type:
    Filetype[PDF - 329.65 KB]
  3. Characteristics of Patients with Oseltamivir-Resistant Pandemic (H1N1) 2009, United States
    Personal Author:
    Graitcer, Samuel B.; Gubareva, Larisa; Kamimoto, Laurie; Doshi, Saumil; Vandermeer, Meredith; Louie, Janice; Waters, Christine; Moore, Zack; Sleeman, Katrina; Okomo-Adhiambo, Margaret; Marshall, Steven A.; St. George, Kirsten; Pan, Chao-Yang; LaPlante, Jennifer M.; Klimov, Alexander; Fry, Alicia M.;
    Published:
    Feb 2011
    Source:
    Emerg Infect Dis. 17(2):255-257.
    Description:
    During April 2009-June 2010, thirty-seven (0.5%) of 6,740 pandemic (H1N1) 2009 viruses submitted to a US surveillance system were oseltamivir resistant. Most patients with oseltamivir-resistant infections were severely immunocompromised (76%) and had...
    File Type:
    Filetype[PDF - 132.32 KB]
  4. Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus Infections, United States, 2010–11
    Personal Author:
    Storms, Aaron D.; Gubareva, Larisa V.; Su, Su; Wheeling, John T.; Okomo-Adhiambo, Margaret; Pan, Chao-Yang; Reisdorf, Erik; St. George, Kirsten; Myers, Robert; Wotton, Jason T.; Robinson, Sara; Leader, Brandon; Thompson, Martha; Shannon, Marjorie; Klimov, Alexander; Fry, Alicia M.;
    Corporate Author:
    for the US Antiviral Resistance Surveillance Working Group
    Published:
    Feb 2012
    Source:
    Emerg Infect Dis. 18(2):308-311.
    Description:
    During October 2010-July 2011, 1.0% of pandemic (H1N1) 2009 viruses in the United States were oseltamivir resistant, compared with 0.5% during the 2009-10 influenza season. Of resistant viruses from 2010-11 and 2009-10, 26% and 89%, respectively, wer...
    File Type:
    Filetype[PDF - 196.14 KB]
  5. Multidrug-Resistant Pandemic (H1N1) 2009 Infection in Immunocompetent Child
    Personal Author:
    Eshaghi, AliReza; Patel, Samir N.; Sarabia, Alicia; Higgins, Rachel R.; Savchenko, Alexei; Stojios, Peter J.; Li, Yan; Bastien, Nathalie; Alexander, David C.; Low, Donald E.; Gubbay, Jonathan B.;
    Published:
    Aug 2011
    Source:
    Emerg Infect Dis. 17(8):1472-1474.
    Description:
    Recent case reports describe multidrug-resistant influenza A pandemic (H1N1) 2009 virus infection in immunocompromised patients exposed to neuraminidase inhibitors because of an I223R neuraminidase mutation. We report a case of multidrug-resistant pa...
    File Type:
    Filetype[PDF - 134.30 KB]