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Molecular Discrimination of Sheep Bovine Spongiform Encephalopathy from Scrapie
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  1. Molecular Typing of Protease-Resistant Prion Protein in Transmissible Spongiform Encephalopathies of Small Ruminants, France, 2002–2009
    Personal Author:
    Vulin, Johann; Biacabe, Anne-Gaëlle; Cazeau, Géraldine; Calavas, Didier; Baron, Thierry;
    Published Date:
    Jan 2011
    Source:
    Emerg Infect Dis. 17(1):55-63.
    Description:
    The agent that causes bovine spongiform encephalopathy (BSE) may be infecting small ruminants, which could have serious implications for human health. To distinguish BSE from scrapie and to examine the molecular characteristics of the protease-resist...
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    Filetype[PDF - 325.95 KB]
  2. Classic Scrapie in Sheep with the ARR/ARR Prion Genotype in Germany and France
    Personal Author:
    Groschup, Martin H.; Lacroux, Caroline; Buschmann, Anne; Lühken, Gesine; Mathey, Jacinthe; Eiden, Martin; Lugan, Séverine; Hoffmann, Christine; Espinosa, Juan Carlos; Baron, Thierry; Torres, Juan Maria; Erhardt, Georg; Andreoletti, Olivier;
    Published Date:
    Aug 2007
    Source:
    Emerg Infect Dis. 13(8):1201-1207.
    Description:
    In the past, natural scrapie and bovine spongiform encephalopathy (BSE) infections have essentially not been diagnosed in sheep homozygous for the A136R154R171 haplotype of the prion protein. This genotype was therefore assumed to confer resistance t...
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  3. Rapid Typing of Transmissible Spongiform Encephalopathy Strains with Differential ELISA
    Personal Author:
    Simon, Stéphanie; Nugier, Jérôme; Morel, Nathalie; Boutal, Hervé; Créminon, Christophe; Benestad, Sylvie L.; Andréoletti, Olivier; Lantier, Frédéric; Bilheude, Jean-Marc; Feyssaguet, Muriel; Biacabe, Anne-Gaëlle; Baron, Thierry; Grassi, Jacques;
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    Apr 2008
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    Emerg Infect Dis. 14(4):608-616.
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    The bovine spongiform encephalopathy (BSE) agent has been transmitted to humans, leading to variant Creutzfeldt-Jakob disease. Sheep and goats can be experimentally infected by BSE and have been potentially exposed to natural BSE; however, whether BS...
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  4. Prion Disease in Dromedary Camels, Algeria
    Personal Author:
    Babelhadj, Baaissa; Di Bari, Michele Angelo; Pirisinu, Laura; Chiappini, Barbara; Gaouar, Semir Bechir Suheil; Riccardi, Geraldina; Marcon, Stefano; Agrimi, Umberto; Nonno, Romolo; Vaccari, Gabriele;
    Published Date:
    Jun 17 2018
    Source:
    Emerg Infect Dis. 24(6):1029-1036.
    Description:
    Prions cause fatal and transmissible neurodegenerative diseases, including Creutzfeldt-Jakob disease in humans, scrapie in small ruminants, and bovine spongiform encephalopathy (BSE). After the BSE epidemic, and the associated human infections, began...
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  5. Transgenic Mice Expressing Porcine Prion Protein Resistant to Classical Scrapie but Susceptible to Sheep Bovine Spongiform Encephalopathy and Atypical Scrapie
    Personal Author:
    Espinosa, Juan-Carlos; Herva, María-Eugenia; Andréoletti, Olivier; Padilla, Danielle; Lacroux, Caroline; Cassard, Hervé; Lantier, Isabelle; Castilla, Joaquin; Torres, Juan-María;
    Published Date:
    Aug 2009
    Source:
    Emerg Infect Dis. 15(8):1214-1221.
    Description:
    How susceptible pigs are to infection with sheep prions is unknown. We show, through transmission experiments in transgenic mice expressing porcine prion protein (PrP), that the susceptibility of this mouse model to bovine spongiform encephalopathy (...
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