Hepatitis A Virus Vaccine Escape Variants and Potential New Serotype Emergence

Pérez-Sautu, Unai; Costafreda, M. Isabel; Caylà, Joan; Tortajada, Cecilia; Lite, Josep; Bosch, Albert; Pintó, Rosa M.

doi:10.3201/eid1704.101169

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

i

Hepatitis A Virus Vaccine Escape Variants and Potential New Serotype Emergence

Apr 2011
By Pérez-Sautu, Unai ; Costafreda, M. Isabel ; Caylà, Joan ; ...
http://dx.doi.org/10.3201/eid1704.101169
Source: Emerg Infect Dis. 17(4):734-737.

[PDF-167.21 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Pérez-Sautu, Unai ; Costafreda, M. Isabel ; Caylà, Joan ; Tortajada, Cecilia ; Lite, Josep ; ... More +

Pérez-Sautu, Unai ; Costafreda, M. Isabel ; Caylà, Joan ; Tortajada, Cecilia ; Lite, Josep ; Bosch, Albert ; Pintó, Rosa M. Less -
Description:

Six hepatitis A virus antigenic variants that likely escaped the protective effect of available vaccines were isolated, mostly from men who have sex with men. The need to complete the proper vaccination schedules is critical, particularly in the immunocompromised population, to prevent the emergence of vaccine-escaping variants.
Subjects:

[+]

Amino Acid Substitution Antigenic Variation Capsid Structural Constraints Codon Usage Dispatch Hepatitis A Hepatitis A Vaccines Hepatitis A Virus Humans Immunocompromised Host Male Molecular Epidemiology Mutation Phylogeny Quasispecies Rare Codon Vaccination Vaccine Escape Mutants Vaccine Escape Variants Viral Structural Proteins Viruses
Source:

Emerg Infect Dis. 17(4):734-737.
Pubmed ID:

21470474
Pubmed Central ID:

PMC3377408
Document Type:

Journal Article
Volume:

17
Issue:

4
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha-512:dbddcd9812274cb2bf035fe10355ea585e8b05444fc14687adbb19151e6a336bb12040c269b6a6db2d800faede7ad45f94f67e6523810457734f3518fc40dfda
Download URL:

https://stacks.cdc.gov/view/cdc/24313/cdc_24313_DS1.pdf
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