NIOSH Testimony on Occupational Exposure to 1,3-Butadiene by J. D. Millar, December 1986.

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  This testimony contains the comments of NIOSH regarding the Advanced Notice of Proposed Rulemaking issues by OSHA in regard to occupational exposures to 1,3-butadiene (106990) (BD). NIOSH continues to recommend that BD be regarded as a potential occupational carcinogen, teratogen, and possible reproductive hazard. NIOSH recommends six studies which should be consulted along these lines. NIOSH is unaware of any studies that have explores the ability of BD to penetrate the skin or that have explored the combined effects of inhalation and dermal exposure. Other aspects considered in the testimony included the methods to be used in estimating the significance of risk at the current exposure level of 1,000 parts per million, particularly mathematical models; the identification of specific quantitative risk assessments of BD; and which tumor incidences in which animal species and by what routes of administration and dose levels should be selected. Concern was also expressed about a possible noncarcinogenic effect of BD on the endocrine system. [Description provided by NIOSH]
• Content Notes:
  in NTRL, no PDF
• Subjects:
  Butadienes Carcinogens Manufacturing And Industrial Facilities Occupational Exposure Occupational Health Rubber Safety
• Keywords:
  NIOSH-Author; NIOSH-Testimony; Millar-J-D; Synthetic-rubbers; Rubber-manufacturing-industry; Rubber-workers; Butadienes; Carcinogenesis; Chemical-manufacturing-industry; Occupational-exposure
• Document Type:
  Text
• Genre:
  Testimony
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-7
• NIOSHTIC Number:
  nn:00196235
• NTIS Accession Number:
  PB91152850
• Citation:
  NIOSH 1986 Dec:7 pages
• CAS Registry Number:
  1,3-Butadiene (CAS RN 106-99-0)
• Federal Fiscal Year:
  1987
• Peer Reviewed:
  False
• Source Full Name:
  NIOSH, 7 pages
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/242972/cdc_242972_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]