Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, South Korea

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Yi, Hwajung ; Lee, Joo-Yeon ; Hong, Eun-Hye ; Kim, Mi-Seon ; Kwon, Donghyok ; Choi, Jang-Hoon ; Choi, Woo-Young ; Kim, Ki-Soon ; Lee, Jong-Koo ; Oh, Hee-Bok ; Kang, Chun
• Description:
  To identify oseltamivir resistance, we analyzed neuraminidase H275Y mutations in samples from 10 patients infected with pandemic (H1N1) 2009 virus in South Korea who had influenza that was refractory to antiviral treatment with this drug. A neuraminidase I117M mutation that might influence oseltamivir susceptibility was detected in sequential specimens from 1 patient.
• Subjects:
  Amino Acid Substitution Antiviral Agents Child, Preschool Disease Outbreaks Drug Resistance, Viral Female Humans Infant Influenza, Human Influenza A Virus, H1N1 Subtype Male Middle Aged Molecular Epidemiology Molecular Sequence Data Neuraminidase Oseltamivir Pandemics Viral Proteins

  More +
• Source:
  Emerg Infect Dis. 16(12):1938-1942.
• Document Type:
  Journal Article
• Place as Subject:
  Republic of Korea
• Volume:
  16
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:5317faa1992650110216857191dd5d8fa17846066928b7cc1530a020c964570c
• Download URL:
  https://stacks.cdc.gov/view/cdc/24264/cdc_24264_DS1.pdf
• File Type:
  [PDF - 432.27 KB ]