Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, South Korea

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Yi, Hwajung ; Lee, Joo-Yeon ; Hong, Eun-Hye ; Kim, Mi-Seon ; Kwon, Donghyok ; Choi, Jang-Hoon ; Choi, Woo-Young ; Kim, Ki-Soon ; Lee, Jong-Koo ; Oh, Hee-Bok ; Kang, Chun
• Description:
  To identify oseltamivir resistance, we analyzed neuraminidase H275Y mutations in samples from 10 patients infected with pandemic (H1N1) 2009 virus in South Korea who had influenza that was refractory to antiviral treatment with this drug. A neuraminidase I117M mutation that might influence oseltamivir susceptibility was detected in sequential specimens from 1 patient.
• Subjects:
  • Amino Acid Substitution
  • Antiviral Agents
  • Child, Preschool
  • Disease Outbreaks
  • Drug Resistance, Viral
  • Female
  • Humans
  • Infant
  • Influenza A Virus, H1N1 Subtype
  • Influenza, Human
  More +
• Source:
  Emerg Infect Dis. 16(12):1938-1942.
• Document Type:
  Journal Article
• Place as Subject:
  Republic of Korea
• Volume:
  16
• Issue:
  12
• Download URL:
  https://stacks.cdc.gov/view/cdc/24264/cdc_24264_DS1.pdf
• File Type:
  [PDF - 432.27 KB]
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:5317faa1992650110216857191dd5d8fa17846066928b7cc1530a020c964570c