Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, South Korea
Published Date:Dec 2010
Source:Emerg Infect Dis. 16(12):1938-1942.
Keywords:Amino Acid Substitution
Drug Resistance, Viral
Influenza A Virus, H1N1 Subtype
Molecular Sequence Data
Republic Of Korea
Description:To identify oseltamivir resistance, we analyzed neuraminidase H275Y mutations in samples from 10 patients infected with pandemic (H1N1) 2009 virus in South Korea who had influenza that was refractory to antiviral treatment with this drug. A neuraminidase I117M mutation that might influence oseltamivir susceptibility was detected in sequential specimens from 1 patient.
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