Development of forced random noise system for the measurement of respiratory impedance. Final Report.

Details

• Personal Author:
  Castellan, Robert M. ; Cocke JB ; Hankinson, John L. ; Sepulveda, Martin-Jose ; Viola JO
• Description:
  Part one of the study called for the design and analysis of a respiratory measurement system employing forced random noise. Respiratory impedance of a human was determined by the administration of a noninvasive test in which random oscillations were superimposed on the respiratory cycle. Spectral analysis was applied to the forcing pressure and resultant flow to arrive at a measure of impedance which is a function of frequency. The measuring system consisted of a random noise source, speaker enclosure, and a portable computer. To isolate physiological (ZL) and respiratory (Zrsp) impedance from measured data, the impedance contributions of the system were determined. With this system, ZL could be determined in less than five minutes with Zrsp isolation taking twice the time. The magnitude and phase of Zrsp for a normal healthy adult were comparable to the results obtained by other studies. In part two of the study lung function responses to inhaled cotton dust were evaluated in a group of 58 healthy subjects by spirometry (MEFV curves) and forced random noise impedance parameters. The data indicate that measures of the Thevenin resistance (real part of impedance) by the forced random noise method are reliable indicators of cotton induced bronchoconstriction. However, measurement variability suggests that these are more appropriate for group studies and should remain adjuncts to standard tests of lung function such as spirometry. [Description provided by NIOSH]
• Content Notes:
  in NTRL, no PDF
• Subjects:
  Dust Gossypium Lung Lung Diseases Manufacturing And Industrial Facilities Occupational Health Respiratory Function Tests Respiratory System Respiratory Tract Diseases Safety
• Keywords:
  NIOSH-Author; Respiratory-system-disorders; Respiration-rate; Respirable-dust; Cotton-mill-workers; Lung-irritants; Pulmonary-function-tests; Pulmonary-congestion
• Document Type:
  Text
• Genre:
  Report
• Place as Subject:
  OSHA Region 3 ; Virginia ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-161
• NIOSHTIC Number:
  nn:00163312
• NTIS Accession Number:
  PB86240439
• Citation:
  NIOSH 1983 Dec; :1-161
• Federal Fiscal Year:
  1984
• NORA Priority Area:
  Disease and Injury: Asthma and Chronic Obstructive Pulmonary Disease
• Peer Reviewed:
  False
• Source Full Name:
  Division of Respiratory Disease Studies, NIOSH, Morgantown, West Virginia
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/242172/cdc_242172_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]