Background information on hexamethylphosphoric triamide.

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  Hexamethylphosphoric-triamide (HMPT) (680319), also known as HMPA, a solvent used in organic and organometallic reactions in laboratories is determined to be tumorigenic, as nasal tumors are observed in rats exposed to the chemical. No data are available on the toxic effects of HMPT in humans, and there is no current OSHA standard for HMPT exposure. Five thousand people are estimated to be occupationally exposed to the compound. A list is given of the major producers and distributors of HMPT. [Description provided by NIOSH]
• Subjects:
  Amides Carcinogens Hazardous Substances Neoplasms Nose Nose Diseases Occupational Health Organophosphates Safety Sense Organs Solvents

  More +
• Keywords:
  NIOSH-Author; Organo-phosphorus-compounds; Organic-solvents; Toxic-substances; Safety-standards; Nasal-cancer; Amides; Tumorigenesis; Carcinogens
• Document Type:
  Text
• Genre:
  Report
• Place as Subject:
  Maryland ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-6
• NIOSHTIC Number:
  nn:00052019
• Citation:
  NIOSH 1975 Oct; :1-6
• CAS Registry Number:
  Hexamethylphosphoramide (CAS RN 680-31-9)
• Federal Fiscal Year:
  1976
• Peer Reviewed:
  False
• Source Full Name:
  Office of Occupational Health Surveillance and Biometrics, NIOSH, Rockville, Maryland, 6 pages, 17 references
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/241926/cdc_241926_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]