Novel Human Reovirus Isolated from Children with Acute Necrotizing Encephalopathy

Ouattara, Louise A.; Barin, Francis; Barthez, Marie Anne; Bonnaud, Bertrand; Roingeard, Philippe; Goudeau, Alain; Castelnau, Pierre; Vernet, Guy; Paranhos-Baccalà, Gláucia; Komurian-Pradel, Florence

doi:10.3201/eid1708.101528

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Novel Human Reovirus Isolated from Children with Acute Necrotizing Encephalopathy

Published Date:

Aug 2011

Publisher's site:

http://dx.doi.org/10.3201/eid1708.101528 New Site Icon

Source:

Emerg Infect Dis. 17(8):1436-1444.

[PDF-413.20 KB]

Details:

Personal Authors:

Ouattara, Louise A. ; Barin, Francis ; Barthez, Marie Anne ; Bonnaud, Bertrand ; Roingeard, Philippe ; ... More ▼

Keywords:

[+]

Description:

For many encephalitis cases, the cause remains unidentified. After 2 children (from the same family) received a diagnosis of acute necrotizing encephalopathy at Centre Hospitalier Universitaire (Tours, France), we attempted to identify the etiologic agent. Because clinical samples from the 2 patients were negative for all pathogens tested, urine and throat swab specimens were added to epithelial cells, and virus isolates detected were characterized by molecular analysis and electron microscopy. We identified a novel reovirus strain (serotype 2), MRV2Tou05, which seems to be closely related to porcine and human strains. A specific antibody response directed against this new reovirus strain was observed in convalescent-phase serum specimens from the patients, whereas no response was observed in 38 serum specimens from 38 healthy adults. This novel reovirus is a new etiologic agent of encephalitis.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

	10-1528-F1.gif	image/gif
	10-1528-F1.jpg	image/jpeg
	10-1528-F2.gif	image/gif
	10-1528-F2.jpg	image/jpeg
	10-1528-F3.gif	image/gif
	10-1528-F3.jpg	image/jpeg
	10-1528-F4.gif	image/gif
	10-1528-F4.jpg	image/jpeg

No Related Documents.

You May Also Like:

Novel Orthoreovirus from Mink, China, 2011

Personal Author:

Lian, Hai; Liu, Ye; Zhang, Shoufeng; Zhang, Fei; Hu, Rongliang;

Published:

Dec 2013

Source:

Emerg Infect Dis. 19(12):1985-1988.

Description:

We identified a novel mink orthoreovirus, MRV1HB-A, which seems to be closely related to human strain MRV2tou05, which was isolated from 2 children with acute necrotizing encephalopathy in 2005. Evolution of this virus should be closely monitored so ...

File Type:

[PDF - 645.74 KB]
Deaths Associated with Pandemic (H1N1) 2009 among Children, Japan, 2009–2010

Personal Author:

Okumura, Akihisa; Nakagawa, Satoshi; Kawashima, Hisashi; Muguruma, Takashi; Saito, Osamu; Fujimoto, Jun-ichi; Toida, Chiaki; Kuga, Shuji; Imamura, Toshihiro; Shimizu, Toshiaki; Kondo, Naomi; Morishima, Tsuneo;

Published:

Nov 2011

Source:

Emerg Infect Dis. 17(11):1993-2000.

Description:

To clarify the cause of deaths associated with pandemic (H1N1) 2009 among children in Japan, we retrospectively studied 41 patients <20 years of age who had died of pandemic (H1N1) 2009 through March 31, 2010. Data were collected through interviews w...

File Type:

[PDF - 253.48 KB]
Isolation of a Novel Fusogenic Orthoreovirus from Eucampsipoda africana Bat Flies in South Africa

Personal Author:

Jansen van Vuren, Petrus; Wiley, Michael; Palacios, Gustavo; Storm, Nadia; McCulloch, Stewart; Markotter, Wanda; Birkhead, Monica; Kemp, Alan; Paweska, Janusz T.;

Published:

Feb 29 2016

Source:

Viruses. 2016; 8(3).

Description:

We report on the isolation of a novel fusogenic orthoreovirus from bat flies (Eucampsipoda africana) associated with Egyptian fruit bats (Rousettus aegyptiacus) collected in South Africa. Complete sequences of the ten dsRNA genome segments of the vir...

File Type:

[PDF - 5.49 MB]
Virulence Potential of Fusogenic Orthoreoviruses

Personal Author:

Wong, Ann H.; Cheng, Peter K.C.; Lai, Mary Y.Y.; Leung, Peter C.K.; Wong, Kitty K.Y.; Lee, W.Y.; Lim, Wilina W.L.;

Published:

Jun 2012

Source:

Emerg Infect Dis. 18(6):944-948.

Description:

Several severe respiratory virus infections that have emerged during the past decade originated in animals, including bats. In Indonesia, exposure to bats has been associated with increased risk of acquiring orthoreovirus infection. Although orthoreo...

File Type:

[PDF - 301.17 KB]
Outbreak-associated Novel Duck Reovirus, China, 2011

Personal Author:

Chen, Zongyan; Zhu, Yinqi; Li, Chuanfeng; Liu, Guangqing;

Published:

Jul 2012

Source:

Emerg Infect Dis. 18(7):1209-1211.

File Type:

[PDF - 135.33 KB]