Enterovirus 68 among Children with Severe Acute Respiratory Infection, the Philippines

Imamura, Tadatsugu; Fuji, Naoko; Suzuki, Akira; Tamaki, Raita; Saito, Mariko; Aniceto, Rapunzel; Galang, Hazel; Sombrero, Lydia; Lupisan, Soccoro; Oshitani, Hitoshi

doi:10.3201/eid1708.101328

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Enterovirus 68 among Children with Severe Acute Respiratory Infection, the Philippines

Published Date:

Aug 2011

Publisher's site:

http://dx.doi.org/10.3201/eid1708.101328 New Site Icon

Source:

Emerg Infect Dis. 17(8):1430-1435.

[PDF - 353.74 KB]

Details:

Personal Authors:

Imamura, Tadatsugu ; Fuji, Naoko ; Suzuki, Akira ; Tamaki, Raita ; Saito, Mariko ; ... More ▼

Keywords:

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Description:

Enterovirus 68 (EV68) is a rare enterovirus associated with respiratory illness that, unlike other enteroviruses, has been identified only from respiratory specimens. We identified EV68 from respiratory specimens of children hospitalized with a diagnosis of severe pneumonia in Leyte, Republic of the Philippines. Twenty-one samples showed high similarity with EV68 by sequencing of 5' nontranslated region; 17 of these samples were confirmed as EV68 by sequencing of viral protein 1 capsid coding region. Most previously reported EV68 cases had been identified as sporadic cases. All 21 patients we identified had severe illness, and 2 died, possibly the first reported fatal cases associated with EV68 infection. Our study suggests that EV68 may be a possible causative agent of severe respiratory illnesses.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

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