Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid1708.101328
Personal Author:
Imamura, Tadatsugu; Fuji, Naoko; Suzuki, Akira; Tamaki, Raita; Saito, Mariko; ... More +
Imamura, Tadatsugu; Fuji, Naoko; Suzuki, Akira; Tamaki, Raita; Saito, Mariko; Aniceto, Rapunzel; Galang, Hazel; Sombrero, Lydia; Lupisan, Soccoro; Oshitani, Hitoshi; Less -
Description:
Enterovirus 68 (EV68) is a rare enterovirus associated with respiratory illness that, unlike other enteroviruses, has been identified only from respiratory specimens. We identified EV68 from respiratory specimens of children hospitalized with a diagnosis of severe pneumonia in Leyte, Republic of the Philippines. Twenty-one samples showed high similarity with EV68 by sequencing of 5' nontranslated region; 17 of these samples were confirmed as EV68 by sequencing of viral protein 1 capsid coding region. Most previously reported EV68 cases had been identified as sporadic cases. All 21 patients we identified had severe illness, and 2 died, possibly the first reported fatal cases associated with EV68 infection. Our study suggests that EV68 may be a possible causative agent of severe respiratory illnesses.
Subject:
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Acute Disease
Adolescent
Child
Child, Preschool
Child Mortality
Enterovirus D, Human
Enterovirus Infections
Female
Hospitalization
Humans
Infant
Infant, Newborn
Male
Molecular Sequence Data
Phylogeny
Pneumonia, Viral
Polymerase Chain Reaction
Sequence Analysis, DNA
Severity Of Illness Index

Source:
Emerg Infect Dis. 17(8):1430-1435.;
Document Type:
Journal Article;
Place as Subject:
Philippines;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:03c8e6cca1aedf3d3fe98d25c010785554cd7f1d15af7939994c00bd9629cb68
File Type:

Supporting Files

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