i
Astrovirus Encephalitis in Boy with X-linked Agammaglobulinemia
-
Published Date:
Jun 2010
Publisher's site:Source:Emerg Infect Dis. 16(6):918-925.Language:English
[PDF-406.86 KB]
Details:-
Alternative Title:Emerg Infect Dis
-
Personal Author:
-
Description:Encephalitis is a major cause of death worldwide. Although >100 pathogens have been identified as causative agents, the pathogen is not determined for up to 75% of cases. This diagnostic failure impedes effective treatment and underscores the need for better tools and new approaches for detecting novel pathogens or determining new manifestations of known pathogens. Although astroviruses are commonly associated with gastroenteritis, they have not been associated with central nervous system disease. Using unbiased pyrosequencing, we detected an astrovirus as the causative agent for encephalitis in a 15-year-old boy with agammaglobulinemia; several laboratories had failed to identify the agent. Our findings expand the spectrum of causative agents associated with encephalitis and highlight unbiased molecular technology as a valuable tool for differential diagnosis of unexplained disease.
-
Subject:
-
Document Type:
-
Funding:
-
Collection(s):
-
Main Document Checksum:
-
File Type:
-
Supporting Files:
text/plain
text/plain 
image/gif 
image/jpeg 
image/gif 
image/jpeg 
image/gif 
image/jpeg 
image/gif 
image/jpeg
No Related Documents. -
[PDF - 179.91 KB]
Published Date:Source:File Type:[PDF - 179.91 KB]
File Type:[PDF - 179.91 KB]
[PDF - 1.10 MB]
Published Date:Source:Description:File Type:[PDF - 1.10 MB]
File Type:[PDF - 1.10 MB]
[PDF - 177.90 KB]
Published Date:Source:Description:File Type:[PDF - 177.90 KB]
File Type:[PDF - 177.90 KB]
[PDF - 323.96 KB]
Published Date:Source:Description:File Type:[PDF - 323.96 KB]
File Type:[PDF - 323.96 KB]
[PDF - 173.70 KB]
Published Date:Source:Description:File Type:[PDF - 173.70 KB]
File Type:[PDF - 173.70 KB]
Email
CDC-INFO
