Secondary and tertiary aliphatic monoamines.

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  The health effects of occupational exposure to secondary and tertiary aliphatic monoamines are reviewed. The extent and degree of exposure through the natural occurrence of aliphatic amines in the environment and by occupational exposure are discussed. Patterns of worker exposure by occupational are described. The biological effect of exposure on humans are discussed, and the results of six epidemiologic studies are presented. A brief description of the toxic effects observed in animal experiments is provided, and limitations in this type of research are discussed. Metabolism studies of these amines are described, and the minimal extent of biochemical studies is noted. The mutagenic and carcinogenic potential and the reproductive effects of secondary and tertiary monoamines are described. Attempts to correlate amine toxicity to chemical structure are discussed, and the correlation of exposure and effect in humans and animals is described. Methods for sampling and analyzing secondary and tertiary aliphatic monoamines in workplace environments are described, and biological monitoring techniques are identified. Employee training, safety procedures, and protective measures are discussed, and engineering control programs to reduce exposure and accidents are described. The authors conclude that these aliphatic amines constitute a real health hazard to workers at current exposure concentrations. [Description provided by NIOSH]
• Content Notes:
  in NTRL, no PDF
• Subjects:
  Epidemiology Fatty Acids Occupational Health Safety Toxicology
• Keywords:
  NIOSH-Contract; Contract-210-79-0091; Worker-health; Epidemiology; Toxicology; Medical-research; Aliphatic-compounds; Industrial-health-programs
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Report
• Place as Subject:
  Maryland ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:00120747
• NTIS Accession Number:
  PB83103614
• Citation:
  NIOSH 1981 Jul; :1-246
• Federal Fiscal Year:
  1981
• Peer Reviewed:
  False
• Source Full Name:
  NIOSH, Franklin Research Center, Silver Spring, 246 pages, 300 references
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/241374/cdc_241374_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]