Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid2007.131587
Personal Author:
Krause, Peter J. ; Narasimhan, Sukanya ; Wormser, Gary P. ; Barbour, Alan G. ; Platonov, Alexander E. ; ... More +
Krause, Peter J. ; Narasimhan, Sukanya ; Wormser, Gary P. ; Barbour, Alan G. ; Platonov, Alexander E. ; Brancato, Janna ; Lepore, Timothy ; Dardick, Kenneth ; Mamula, Mark ; Rollend, Lindsay ; Steeves, Tanner K. ; Diuk-Wasser, Maria ; Usmani-Brown, Sahar ; Williamson, Phillip ; Sarksyan, Denis S. ; Fikrig, Erol ; Fish, Durland ; Less -
Corporate Authors:
Tick Borne Diseases Group ;
Description:
Borrelia miyamotoi sensu lato, a relapsing fever Borrelia sp., is transmitted by the same ticks that transmit B. burgdorferi (the Lyme disease pathogen) and occurs in all Lyme disease-endemic areas of the United States. To determine the seroprevalence of IgG against B. miyamotoi sensu lato in the northeastern United States and assess whether serum from B. miyamotoi sensu lato-infected persons is reactive to B. burgdorferi antigens, we tested archived serum samples from area residents during 1991-2012. Of 639 samples from healthy persons, 25 were positive for B. miyamotoi sensu lato and 60 for B. burgdorferi. Samples from ≈10% of B. miyamotoi sensu lato-seropositive persons without a recent history of Lyme disease were seropositive for B. burgdorferi. Our results suggest that human B. miyamotoi sensu lato infection may be common in southern New England and that B. burgdorferi antibody testing is not an effective surrogate for detecting B. miyamotoi sensu lato infection.
Subject:
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Antibodies, Bacterial
Borrelia
Borrelia Infections
Female
Humans
Immunoglobulin G
Lyme Disease
Male
Middle Aged
Research
Seroepidemiologic Studies

Source:
Emerg Infect Dis. 20(7):1183-1190.
Document Type:
Journal Article ;
Place as Subject:
New England ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:f786a70ce2597503765e7f6d7bc3c94462d37956d3c21c4d1c8887c6a4771b13
File Type:

Supporting Files

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