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Use of Spatial Information to Predict Multidrug Resistance in Tuberculosis Patients, Peru
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    Cohen, Ted; Murray, Megan; Abubakar, Ibrahim; Zhang, Zibiao; Sloutsky, Alexander; Arteaga, Fernando; Chalco, Katiuska; Franke, Molly F.; Becerra, Mercedes C.;
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    Source:
    Emerg Infect Dis. 17(6):969-975.
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    Two cases of multidrug-resistant tuberculosis (MDR TB) in a household are assumed to reflect within-household transmission. However, in high-incidence areas of MDR TB, secondary cases may arise through exposure to MDR TB in the community. To estimate...
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  2. Association between Regimen Composition and Treatment Response in Patients with Multidrug-Resistant Tuberculosis: A Prospective Cohort Study
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    Yuen, Courtney M.; Kurbatova, Ekaterina V.; Tupasi, Thelma; Caoili, Janice Campos; Van Der Walt, Martie; Kvasnovsky, Charlotte; Yagui, Martin; Bayona, Jaime; Contreras, Carmen; Leimane, Vaira; Ershova, Julia; Via, Laura E.; Kim, HeeJin; Akksilp, Somsak; Kazennyy, Boris Y.; Volchenkov, Grigory V.; Jou, Ruwen; Kliiman, Kai; Demikhova, Olga V.; Vasilyeva, Irina A.; Dalton, Tracy; Cegielski, J. Peter;
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    Background : For treating multidrug-resistant tuberculosis (MDR TB), the World Health Organization (WHO) recommends a regimen of at least four second-line drugs that are likely to be effective as well as pyrazinamide. WHO guidelines indicate only mar...
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    United States. Agency for International Development.; National Institute of Allergy and Infectious Diseases (U.S.); Centers for Disease Control and Prevention (U.S.);
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    NAP-MDR-TB-Year-Two-508.pdf
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  4. Bedaquiline and Delamanid Combination Treatment of 5 Patients with Pulmonary Extensively Drug-Resistant Tuberculosis
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    Maryandyshev, Andrey; Pontali, Emanuele; Tiberi, Simon; Akkerman, Onno; Ganatra, Shashank; Sadutshang, Tsetan Dorji; Alffenaar, Jan-Willem; Amale, Rohit; Mullerpattan, Jai; Topgyal, Sonam; Udwadia, Zarir Farokh; Centis, Rosella; D’Ambrosio, Lia; Sotgiu, Giovanni; Migliori, Giovanni Battista;
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    Emerg Infect Dis. 23(10):1718-1721.
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    We report the experiences of 5 patients taking bedaquiline with delamanid in combination: 1 patient was cured; 3 culture converted, with 2 continuing and 1 changing therapy; and 1 died from respiratory insufficiency. For 2 patients, QT-interval prolo...
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  5. Scale-up of Multidrug-Resistant Tuberculosis Laboratory Services, Peru
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    Shin, Sonya S.; Yagui, Martin; Ascencios, Luis; Yale, Gloria; Suarez, Carmen; Quispe, Neyda; Bonilla, Cesar; Blaya, Joaquin; Taylor, Allison; Contreras, Carmen; Cegielski, Peter;
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    May 2008
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    Emerg Infect Dis. 14(5):701-708.
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    Over the past 10 years, the Peruvian National Tuberculosis (TB) Program, the National Reference Laboratory (NRL), Socios en Salud, and US partners have worked to strengthen the national TB laboratory network to support treatment of multidrug-resistan...
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