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Use of Spatial Information to Predict Multidrug Resistance in Tuberculosis Patients, Peru
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  1. Where is tuberculosis transmission happening? Insights from the literature, new tools to study transmission and implications for the elimination of tuberculosis
    Personal Author:
    AULD, Sara C.; SHAH, N. Sarita; COHEN, Ted; MARTINSON, Neil A.; GANDHI, Neel R.;
    Published Date:
    June 05 2018
    Source:
    Respirology.
    Description:
    More than 10 million new cases of tuberculosis (TB) are diagnosed worldwide each year. The majority of these cases occur in low- and middle-income countries where the TB epidemic is predominantly driven by transmission. Efforts to 'end TB' will depen...
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  2. Multiple Introductions of Multidrug-Resistant Tuberculosis into Households, Lima, Peru
    Personal Author:
    Cohen, Ted; Murray, Megan; Abubakar, Ibrahim; Zhang, Zibiao; Sloutsky, Alexander; Arteaga, Fernando; Chalco, Katiuska; Franke, Molly F.; Becerra, Mercedes C.;
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    Jun 2011
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    Emerg Infect Dis. 17(6):969-975.
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    Two cases of multidrug-resistant tuberculosis (MDR TB) in a household are assumed to reflect within-household transmission. However, in high-incidence areas of MDR TB, secondary cases may arise through exposure to MDR TB in the community. To estimate...
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  3. Association between Regimen Composition and Treatment Response in Patients with Multidrug-Resistant Tuberculosis: A Prospective Cohort Study
    Personal Author:
    Yuen, Courtney M.; Kurbatova, Ekaterina V.; Tupasi, Thelma; Caoili, Janice Campos; Van Der Walt, Martie; Kvasnovsky, Charlotte; Yagui, Martin; Bayona, Jaime; Contreras, Carmen; Leimane, Vaira; Ershova, Julia; Via, Laura E.; Kim, HeeJin; Akksilp, Somsak; Kazennyy, Boris Y.; Volchenkov, Grigory V.; Jou, Ruwen; Kliiman, Kai; Demikhova, Olga V.; Vasilyeva, Irina A.; Dalton, Tracy; Cegielski, J. Peter;
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    Dec 29 2015
    Source:
    PLoS Med. 12(12).
    Description:
    BackgroundFor treating multidrug-resistant tuberculosis (MDR TB), the World Health Organization (WHO) recommends a regimen of at least four second-line drugs that are likely to be effective as well as pyrazinamide. WHO guidelines indicate only margin...
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  4. National Action Plan for Combating Multidrug-Resistant Tuberculosis : year two report May 2018
    Corporate Authors:
    United States. Agency for International Development.. National Institute of Allergy and Infectious Diseases (U.S.). Centers for Disease Control and Prevention (U.S.).
    Published Date:
    May 2018
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    NAP-MDR-TB-Year-Two-508.pdf
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  5. Bedaquiline and Delamanid Combination Treatment of 5 Patients with Pulmonary Extensively Drug-Resistant Tuberculosis
    Personal Author:
    Maryandyshev, Andrey; Pontali, Emanuele; Tiberi, Simon; Akkerman, Onno; Ganatra, Shashank; Sadutshang, Tsetan Dorji; Alffenaar, Jan-Willem; Amale, Rohit; Mullerpattan, Jai; Topgyal, Sonam; Udwadia, Zarir Farokh; Centis, Rosella; D’Ambrosio, Lia; Sotgiu, Giovanni; Migliori, Giovanni Battista;
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    Oct 17 2017
    Source:
    Emerg Infect Dis. 23(10):1718-1721.
    Description:
    We report the experiences of 5 patients taking bedaquiline with delamanid in combination: 1 patient was cured; 3 culture converted, with 2 continuing and 1 changing therapy; and 1 died from respiratory insufficiency. For 2 patients, QT-interval prolo...
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