Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid1805.110812
Personal Author:
Petersen, Randi Føns ; Dalby, Tine ; Dragsted, Ditte Marie ; Mooi, Frits ; Lambertsen, Lotte ;
Petersen, Randi Føns ; Dalby, Tine ; Dragsted, Ditte Marie ; Mooi, Frits ; Lambertsen, Lotte ; Less -
Description:
We used multilocus variable-number tandem repeat analysis and multiple antigen sequence typing to characterize isolates of Bordetella pertussis strains circulating in Denmark during periods with and without pertussis vaccination coverage. Our results show substantial shifts in the B. pertussis population over time and a reduction in genetic diversity. These changes might have resulted from the introduction of pertussis vaccines in Denmark and other parts of Europe. The predominant strains currently circulating in Denmark resemble those in other European countries.
Subject:
[+]
Alleles
Bacteria
Bordetella Pertussis
Denmark
DNA, Bacterial
Gene Frequency
Genetic Variation
Humans
MAST
MLVA
Multilocus Sequence Typing
Multilocus Variable-number Tandem Repeat Analysis
Multiple Antigen Sequence Typing
Pertussis Vaccine
Prn
PtxA
PtxP
Research
Tandem Repeat Sequences
TcfA
Vaccination
Whooping Cough
Whooping Cough

Source:
Emerg Infect Dis. 18(5):767-774. ;
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:f8f09e3aa7da133be538f48e6ca28d6215b25c3e26f94b05e5a66968348684ae
File Type:

Supporting Files

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