Temporal Trends in Bordetella pertussis Populations, Denmark, 1949–2010
Published Date:May 2012
Source:Emerg Infect Dis. 18(5):767-774.
Multilocus Sequence Typing
Multilocus Variable-number Tandem Repeat Analysis
Multiple Antigen Sequence Typing
Tandem Repeat Sequences
Description:We used multilocus variable-number tandem repeat analysis and multiple antigen sequence typing to characterize isolates of Bordetella pertussis strains circulating in Denmark during periods with and without pertussis vaccination coverage. Our results show substantial shifts in the B. pertussis population over time and a reduction in genetic diversity. These changes might have resulted from the introduction of pertussis vaccines in Denmark and other parts of Europe. The predominant strains currently circulating in Denmark resemble those in other European countries.
image/gif image/jpeg image/gif image/jpeg image/gif image/jpeg image/gif image/jpeg text/plain text/plain
You May Also Like: