Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Tyrrell, Gregory J. ; Lovgren, Marguerite ; Ibrahim, Quazi ; Garg, Sipi ; Chui, Linda ; ... More +
Tyrrell, Gregory J. ; Lovgren, Marguerite ; Ibrahim, Quazi ; Garg, Sipi ; Chui, Linda ; Boone, Tyler J. ; Mangan, Carol ; Patrick, David M. ; Hoang, Linda ; Horsman, Greg B. ; Van Caeseele, Paul ; Marrie, Thomas J. Less -
Description:
In Canada before 2005, large outbreaks of pneumococcal disease, including invasive pneumococcal disease caused by serotype 5, were rare. Since then, an epidemic of serotype 5 invasive pneumococcal disease was reported: 52 cases during 2005, 393 during 2006, 457 during 2007, 104 during 2008, and 42 during in 2009. Of these 1,048 cases, 1,043 (99.5%) occurred in the western provinces of Canada. Median patient age was 41 years, and most (659 [59.3%]) patients were male. Most frequently representing serotype 5 cases (compared with a subset of persons with non-serotype 5 cases) were persons who were of First Nations heritage or homeless. Restriction fragment-length polymorphism typing indicated that the epidemic was caused by a single clone, which multilocus sequence typing identified as sequence type 289. Large pneumococcal epidemics might go unrecognized without surveillance programs to document fluctuations in serotype prevalence.
Subjects:
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Adult Aged Epidemics Female Humans Male Middle Aged Multilocus Sequence Typing Pneumococcal Infections Prevalence Serotyping Young Adult
Source:
Emerg Infect Dis. 18(5):733-740.
Document Type:
Journal Article
Place as Subject:
Canada
Location:
North America
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:fafd58dd77e61089a91cfceda70d56f8750bda3128b049acf64e9ea6b1eeee4d
Download URL:
https://stacks.cdc.gov/view/cdc/23893/cdc_23893_DS1.pdf
File Type:

Supporting Files

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