Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid1804.110912
Personal Author:
de Steenwinkel, Jurriaan E.M. ; ten Kate, Marian T. ; de Knegt, Gerjo J. ; Kremer, Kristin ; Aarnoutse, Rob E. ; ... More +
de Steenwinkel, Jurriaan E.M. ; ten Kate, Marian T. ; de Knegt, Gerjo J. ; Kremer, Kristin ; Aarnoutse, Rob E. ; Boeree, Martin J. ; Verbrugh, Henri A. ; van Soolingen, Dick ; Bakker-Woudenberg, Irma A.J.M. ; Less -
Description:
To determine differences in the ability of Mycobacterium tuberculosis strains to withstand antituberculosis drug treatment, we compared the activity of antituberculosis drugs against susceptible Beijing and East-African/Indian genotype M. tuberculosis strains. Beijing genotype strains showed high rates of mutation within a wide range of drug concentrations, possibly explaining this genotype's association with multidrug-resistant tuberculosis.
Subject:
[+]
Amikacin
Antimicrobial Resistances
Antitubercular Agents
Antituberculosis Drugs
Aza Compounds
Bacterial Proteins
Beijing Genotype Strains
Dispatch
Drug Resistance, Multiple, Bacterial
Emergence
Genotype
Isoniazid
MDR TB
Microbial Sensitivity Tests
Multidrug-resistant Tuberculosis
Mutation
Mycobacterium Tuberculosis
Quinolines
Resistance
Rifampin
Statistics, Nonparametric
Tuberculosis, Multidrug-Resistant
Tuberculosis And Other Mycobacteria

Source:
Emerg Infect Dis. 18(4):660-663. ;
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:250a67ff0076fc6d017059c38912f9849e52ae6b3f985725726b05a6112b317a
File Type:

Supporting Files

• 	license.txt	txt
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  	11-0912-F1.jpg	jpeg
  	11-0912-F2.gif	gif
  	11-0912-F2.jpg	jpeg
  	11-0912-Techapp_4p.pdf	pdf
  	11-0912_finalD.nxml	txt

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