Drug Susceptibility of Mycobacterium tuberculosis Beijing Genotype and Association with MDR TB
Published Date:Apr 2012
Source:Emerg Infect Dis. 18(4):660-663.
Beijing Genotype Strains
Drug Resistance, Multiple, Bacterial
Microbial Sensitivity Tests
Tuberculosis And Other Mycobacteria
Description:To determine differences in the ability of Mycobacterium tuberculosis strains to withstand antituberculosis drug treatment, we compared the activity of antituberculosis drugs against susceptible Beijing and East-African/Indian genotype M. tuberculosis strains. Beijing genotype strains showed high rates of mutation within a wide range of drug concentrations, possibly explaining this genotype's association with multidrug-resistant tuberculosis.
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