Geographic Distribution of Endemic Fungal Infections among Older Persons, United States1

Baddley, John W.; Winthrop, Kevin L.; Patkar, Nivedita M.; Delzell, Elizabeth; Beukelman, Timothy; Xie, Fenglong; Chen, Lang; Curtis, Jeffrey R.

doi:10.3201/eid1709.101987

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Geographic Distribution of Endemic Fungal Infections among Older Persons, United States1

Published Date:

Sep 2011

Publisher's site:

http://dx.doi.org/10.3201/eid1709.101987 New Site Icon

Source:

Emerg Infect Dis. 17(9):1664-1669.

[PDF-274.36 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Baddley, John W. ; Winthrop, Kevin L. ; Patkar, Nivedita M. ; Delzell, Elizabeth ; Beukelman, Timothy ; ... More ▼

Description:

To investigate the epidemiology and geographic distribution of histoplasmosis, coccidioidomycosis, and blastomycosis in older persons in the United States, we evaluated a random 5% sample of national Medicare data from 1999 through 2008. We calculated national, regional, and state-based incidence rates and determined 90-day postdiagnosis mortality rates. We identified 776 cases (357 histoplasmosis, 345 coccidioidomycosis, 74 blastomycosis). Patient mean age was 75.7 years; 55% were male. Histoplasmosis and blastomycosis incidence was highest in the Midwest (6.1 and 1.0 cases/100,000 person-years, respectively); coccidioidomycosis incidence rate was highest in the West (15.2). On the basis of available data, for 86 (11.1%) cases, there was no patient exposure to a traditional disease-endemic area. Knowledge of areas where endemic mycosis incidence is increased may affect diagnostic or prevention measures for older adults at risk.

Subject:

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Document Type:

Journal Article

Funding:

R01HS018517/HS/AHRQ HHS/United States

Collection(s):

Emerging Infectious Diseases

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