Geographic Distribution of Endemic Fungal Infections among Older Persons, United States1

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Baddley, John W. ; Winthrop, Kevin L. ; Patkar, Nivedita M. ; Delzell, Elizabeth ; Beukelman, Timothy ; Xie, Fenglong ; Chen, Lang ; Curtis, Jeffrey R.
• Description:
  To investigate the epidemiology and geographic distribution of histoplasmosis, coccidioidomycosis, and blastomycosis in older persons in the United States, we evaluated a random 5% sample of national Medicare data from 1999 through 2008. We calculated national, regional, and state-based incidence rates and determined 90-day postdiagnosis mortality rates. We identified 776 cases (357 histoplasmosis, 345 coccidioidomycosis, 74 blastomycosis). Patient mean age was 75.7 years; 55% were male. Histoplasmosis and blastomycosis incidence was highest in the Midwest (6.1 and 1.0 cases/100,000 person-years, respectively); coccidioidomycosis incidence rate was highest in the West (15.2). On the basis of available data, for 86 (11.1%) cases, there was no patient exposure to a traditional disease-endemic area. Knowledge of areas where endemic mycosis incidence is increased may affect diagnostic or prevention measures for older adults at risk.
• Subjects:
  Aged Blastomycosis Coccidioidomycosis Endemic Diseases Female Histoplasmosis Humans Incidence Male Retrospective Studies
• Source:
  Emerg Infect Dis. 17(9):1664-1669.
• Document Type:
  Journal Article
• Funding:
  R01HS018517/HS/AHRQ HHS/United States
• Place as Subject:
  United States
• Location:
  North America
• Volume:
  17
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:155c9632248f8cac1bcf8599172965bd1b7ddb8204d415f7a00e874a4c38d0f7
• Download URL:
  https://stacks.cdc.gov/view/cdc/23683/cdc_23683_DS1.pdf
• File Type:
  [PDF - 274.36 KB ]