CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.
As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
i
Mutations I117V and I117M and Oseltamivir Sensitivity of Pandemic (H1N1) 2009 Viruses
-
Jan 2012
-
-
Source: Emerg Infect Dis. 18(1):109-112.
Details:
-
Alternative Title:Emerg Infect Dis
-
Personal Author:
-
Description:Analysis of mutations I117V and I117M in the neuraminidase of influenza A pandemic (H1N1) 2009 viruses showed that I117V confers a mild reduction in oseltamivir sensitivity and has a synergistic effect of further increasing resistance when combined with H275Y. Contrary to recent reports, the I117M mutation does not alter oseltamivir sensitivity.
-
Subjects:
-
Source:
-
Document Type:
-
Volume:18
-
Issue:1
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type: