Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid1801.110784
Personal Author:
Campbell, Helen ; Amirthalingam, Gayatri ; Andrews, Nick ; Fry, Norman K. ; George, Robert C. ; ... More +
Campbell, Helen ; Amirthalingam, Gayatri ; Andrews, Nick ; Fry, Norman K. ; George, Robert C. ; Harrison, Timothy G. ; Miller, Elizabeth Less -
Description:
Results of an accelerated pertussis vaccination schedule for infants introduced in 1990 in England and Wales were examined. Earlier scheduling and sustained high vaccine coverage resulted in fewer reported cases of pertussis among infants, reinforcing the World Health Organization drive for on-time completion of the infant vaccination schedule. As determined by using the screening method, the first dose of vaccine was 61.7% effective in infants <6 months of age, and effectiveness increased with subsequent doses. Three doses of a good whole-cell pertussis vaccine were 83.7% effective in children 10-16 years of age; a preschool booster vaccination further reduced pertussis incidence in children <10 years of age. As in other industrialized countries, surveillance data during 1998-2009 showed that pertussis in England and Wales mainly persists in young infants (i.e., <3 months of age), teenagers, and adults. Future vaccine program changes may be beneficial, but additional detail is required to inform such decisions.
Subject:
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Adolescent
Child
Child, Preschool
Communicable Disease Control
History, 20th Century
History, 21st Century
Humans
Immunization, Secondary
Immunization Schedule
Infant
Pertussis Vaccine
Population Surveillance
Time Factors
Whooping Cough

Source:
Emerg Infect Dis. 18(1):38-47.
Document Type:
Journal Article
Place as Subject:
England ; Wales
England ; Wales Less -
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:15c1bd331d1323b88660af97d3fe8c1c49d65cf4d28bcb2f5d0704f8bea6814a
File Type:

Supporting Files

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