Candida spp. with Acquired Echinocandin Resistance, France, 2004–20101
Published Date:Jan 2012
Source:Emerg Infect Dis. 18(1):86-90.
Corporate Authors:French Mycoses Study Group
Aged, 80 And Over
Drug Resistance, Fungal
Microbial Sensitivity Tests
Description:We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related.
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