Human Gyrovirus DNA in Human Blood, Europe

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Maggi, Fabrizio ; Macera, Lisa ; Focosi, Daniele ; Vatteroni, Maria Linda ; Boggi, Ugo ; Antonelli, Guido ; Eloit, Marc ; Pistello, Mauro
• Description:
  Human gyrovirus (HGyV) is a recent addition to the list of agents found in humans. Prevalence, biologic properties, and clinical associations of this novel virus are still incompletely understood. We used qualitative PCRs to detect HGyV in blood samples of 301 persons from Europe. HGyV genome was detected in 3 of 100 solid organ transplant recipients and in 1 HIV-infected person. The virus was not detected in plasma samples from healthy persons. Furthermore, during observation, persons for whom longitudinal plasma samples were obtained had transient and scattered presence of circulating HGyV. Sequencing of a 138-bp fragment showed nucleotide identity among all the HGyV isolates. These results show that HGyV can be present in the blood of infected persons. Additional studies are needed to investigate possible clinical implications.
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Blood Circoviridae Infections DNA, Viral Europe Female Gyrovirus HGyV DNA HIV Human Gyrovirus Humans Longitudinal Studies Male Middle Aged Polymerase Chain Reaction Prevalence Real-time PCR Research Sequence Analysis, DNA Sequencing Transplantation Viremia Viruses Young Adult

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• Source:
  Emerg Infect Dis. 18(6):956-959.
• Document Type:
  Journal Article
• Volume:
  18
• Issue:
  6
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:4a014f18c136d2e914cae2122b62cfdce28500e9559d4753dc30c78f4502f2dd
• Download URL:
  https://stacks.cdc.gov/view/cdc/23599/cdc_23599_DS1.pdf
• File Type:
  [PDF - 204.86 KB ]