Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid1806.120091
Personal Author:
Guillot, Sophie ; Descours, Ghislaine ; Gillet, Yves ; Etienne, Jérome ; Floret, Daniel ; ... More +
Guillot, Sophie ; Descours, Ghislaine ; Gillet, Yves ; Etienne, Jérome ; Floret, Daniel ; Guiso, Nicole Less -
Description:
A macrolide antimicrobial drug was administered to a newborn with cough. On day 23 of hospitalization, macrolide-resistant Bordetella pertussis was isolated from nasopharyngeal aspirates. DNA sequencing and PCR-restriction fragment length polymorphism showed a 2047 A-to-G mutation in the 3 copies of the 23S rRNA gene. Monitoring for macrolide resistance is essential in infants <6 months of age.
Subjects:
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Adolescents Antibacterial Drugs Antimicrobial Resistance Azithromycin Bacteria Bordetella Pertussis Children Clarithromycin Dispatch DNA Mutational Analysis Drug Resistance, Bacterial Exchange Transfusion, Whole Blood Female France Humans Infant, Newborn Infants Macrolide Resistance Newborn Respiratory Infections Rna, Ribosomal, 23S Treatment Outcome Whooping Cough
Source:
Emerg Infect Dis. 18(6):966-968.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:c96f1d0b65e8879c1707d0f296ed17ac3be243f586b9fe70350af053bfc693e9
Download URL:
https://stacks.cdc.gov/view/cdc/23594/cdc_23594_DS1.pdf
File Type:

Supporting Files

• 	12-0091-F.gif	gif
  	12-0091-F.jpg	jpeg
  	12-0091_finalD.nxml	txt
  	license.txt	txt

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