Macrolide-Resistant Bordetella pertussis Infection in Newborn Girl, France

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Guillot, Sophie ; Descours, Ghislaine ; Gillet, Yves ; Etienne, Jérome ; Floret, Daniel ; Guiso, Nicole
• Description:
  A macrolide antimicrobial drug was administered to a newborn with cough. On day 23 of hospitalization, macrolide-resistant Bordetella pertussis was isolated from nasopharyngeal aspirates. DNA sequencing and PCR-restriction fragment length polymorphism showed a 2047 A-to-G mutation in the 3 copies of the 23S rRNA gene. Monitoring for macrolide resistance is essential in infants <6 months of age.
• Subjects:
  Adolescents Antibacterial Drugs Antimicrobial Resistance Azithromycin Bacteria Bordetella Pertussis Children Clarithromycin Dispatch DNA Mutational Analysis Drug Resistance, Bacterial Exchange Transfusion, Whole Blood Female France Humans Infant, Newborn Infants Macrolide Resistance Newborn Respiratory Infections Rna, Ribosomal, 23S Treatment Outcome Whooping Cough

  More +
• Source:
  Emerg Infect Dis. 18(6):966-968.
• Document Type:
  Journal Article
• Volume:
  18
• Issue:
  6
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:c96f1d0b65e8879c1707d0f296ed17ac3be243f586b9fe70350af053bfc693e9
• Download URL:
  https://stacks.cdc.gov/view/cdc/23594/cdc_23594_DS1.pdf
• File Type:
  [PDF - 276.65 KB ]