Immunodeficiency-associated Vaccine-Derived Poliovirus Type 3 in Infant, South Africa, 2011

Gumede, Nicksy; Muthambi, Vongani; Schoub, Barry D.

doi:10.3201/eid1806.120037

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Immunodeficiency-associated Vaccine-Derived Poliovirus Type 3 in Infant, South Africa, 2011

Published Date:

Jun 2012

Publisher's site:

http://dx.doi.org/10.3201/eid1806.120037 New Site Icon

Source:

Emerg Infect Dis. 18(6):992-994.

[PDF - 238.82 KB]

Details:

Personal Authors:

Gumede, Nicksy ; Muthambi, Vongani ; Schoub, Barry D. ;

Keywords:

[+]

Description:

Patients with primary immunodeficiency are prone to persistently excrete Sabin-like virus after administration of live-attenuated oral polio vaccine and have an increased risk for vaccine-derived paralytic polio. We report a case of type 3 immunodeficiency-associated vaccine-derived poliovirus in a child in South Africa who was born with X-linked immunodeficiency syndrome.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

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