Spirometric Transition Probabilities in Former World Trade Center (WTC) Workers and Volunteers

Details

• Personal Author:
  Celedon JC ; de la Hoz RE ; Doucette JT ; Sood A ; Weber J
• Description:
  Background: Workers and volunteers who participated in the rescue and recovery of the World Trade Center (WTC) disaster site in 2001 -2002 manifest a heterogenous group 01 chronic lower airway diseases, with variable spirometric patterns. We examined systematically the observed transitions among those spirometric patterns. Methods: from the WTC Chest Imaging Archive cohort (n=1641), we selected a group of 624 former WTC rescue and recovery workers with at least 3 periodic spirometries with bronchodilator (BD) testing performed between 2002 and 2017. We used the NHANES-I11 prediction equations, to derive four spirometric categories: (1) normal: pre-BD FEV 1 FVC. and FEV 1/FVC ratio>lower limit of normal (LLN): (2) COPD/fixed obstruction: post-BD FEV1/FVC ratio<0.7: (3) low FVC: FVC
• Subjects:
  Cohort Studies Emergency Responders Lung Occupational Health Respiratory Function Tests Respiratory System Safety September 11 Terrorist Attacks
• Keywords:
  Chronic Obstructive Pulmonary Disease Cohort Studies COPD Emergency Responders Lung Function Rescue Workers Spirometry World Trade Center WTC
• ISSN:
  1073-449X
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Abstract or Summary
• Place as Subject:
  New Mexico ; New York ; OSHA Region 2 ; OSHA Region 3 ; OSHA Region 6 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  201
• NIOSHTIC Number:
  nn:20066948
• Citation:
  Am J Respir Crit Care Med 2020 May; 201(Abstract Issue):A7133
• Email:
  Rafael.delaHoz@mssm.edu
• Federal Fiscal Year:
  2020
• Performing Organization:
  Icahn School of Medicine at Mount Sinai, New York
• Peer Reviewed:
  False
• Start Date:
  20180701
• Source Full Name:
  American Journal of Respiratory and Critical Care Medicine
• Supplement:
  Abstract Issue
• End Date:
  20210630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:76c4f180d7328293a6ca393790cb057ff63cbab93f994833d6fc7594ef2daa678692830700ac869396b70a021fac2ff6ca2c3358eaf4cf97347cf97a4c7487db
• Download URL:
  https://stacks.cdc.gov/view/cdc/231223/cdc_231223_DS1.pdf
• File Type:
  [PDF - 153.84 KB ]