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PCR for Detection of Oseltamivir Resistance Mutation in Influenza A(H7N9) Virus
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May 2014
Source: Emerg Infect Dis. 20(5):847-849. -
Alternative Title:Emerg Infect Dis
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Description:Sensitive molecular techniques are needed for rapid detection of the R292K oseltamivir-resistant mutant of influenza A(H7/N9) virus strain to monitor its transmission and guide antiviral treatment. We developed a real-time reverse transcription PCR and single nucleotide polymorphism probes to differentiate this mutant strain in mixed virus populations in human specimens.
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