The Development of a WTC Environmental Health Center Pan-Cancer Database

Details

• Personal Author:
  Abbott SA ; Addessi A ; Arslan AA ; Corona R ; Durmus N ; Fernandez-Beros M-E ; Pehlivan S ; Reibman J ; Shao Y ; Smyth-Giambanco S ; Umana L ; Zhang Y
• Description:
  (1) Background: Recent studies have reported elevated risks of multiple cancers in the World Trade Center (WTC) affected community members (also called WTC "Survivors"). The large variety of WTC-cancers created a need to develop a comprehensive cancer database. This paper describes the development of a pan-cancer database at the WTC Environmental Health Center (EHC) Data Center. (2) Methods: A new REDCap-based pan-cancer database was created using the pathology reports and available biomarker data of confirmed cancer cases after review by a cancer epidemiologist, a pathologist, physicians and biostatisticians. (3) Results: The WTC EHC pan-cancer database contains cancer characteristics and emerging biomarker information for cancers of individuals enrolled in the WTC EHC and diagnosed after 11 September 2001 and up to 31 December 2019 obtained from WTC EHC clinical records, pathological reports and state cancer registries. As of 31 December 2019, the database included 3440 cancer cases with cancer characteristics and biomarker information. (4) Conclusions: This evolving database represents an important resource for the scientific community facilitating future research about the etiology, heterogeneity, characteristics and outcomes of cancers and comorbid mental health conditions, cancer economics and gene-environment interaction in the unique population of WTC survivors. [Description provided by NIOSH]
• Subjects:
  Biomarkers Database Epidemiology Neoplasms Occupational Health Safety September 11 Terrorist Attacks
• Keywords:
  Author Keywords: Cancer Incidence Biostatistics Cancer Rates Clinical Cancer Database Databases September 11th Surveillance Programs World Trade Center WTC WTC Environmental Health Center WTC Survivors

  More +
• ISSN:
  1660-4601
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  18
• Issue:
  4
• NIOSHTIC Number:
  nn:20068150
• Citation:
  Int J Environ Res Public Health 2021 Feb; 18(4):1646
• Contact Point Address:
  Yongzhao Shao, Division of Biostatistics, Department of Population Health, NYU Grossman School of Medicine (NYUGSOM), New York University, New York, NY 10016, USA
• Email:
  zhao.shao@nyulangone.org
• Federal Fiscal Year:
  2021
• Performing Organization:
  NYC Health + Hospitals (H+H): NYC H+H Data Center
• Peer Reviewed:
  True
• Start Date:
  20170401
• Source Full Name:
  International Journal of Environmental Research and Public Health
• End Date:
  20210331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:479b81725c5c9cbece12dad3f969b120972675afbaaf43036c3338ff78bc485b00554d8947af29951f09a72599af3e449ec01f41db814e7dae15d54819d9b6b6
• Download URL:
  https://stacks.cdc.gov/view/cdc/230364/cdc_230364_DS1.pdf
• File Type:
  [PDF - 1.08 MB ]