Association of Occupational Exposures and Chronic Obstructive Pulmonary Disease Morbidity

Details

• Personal Author:
  Barr RG ; Buckley JP ; Comellas AP ; Cooper CB ; Dransfield MT ; Drummond MB ; Han MK ; Hansel NN ; Hoffman EA ; Kanner RE ; Koehler K ; Labaki W ; Lees PSJ ; Paine R III ; Paulin LM ; Peters SP ; Pirozzi C ; Putcha N ; Quirós-Alcalá L ; Rous JS
• Description:
  Objective: The aim of the study is to determine whether aggregate measures of occupational exposures are associated with chronic obstructive pulmonary disease (COPD) outcomes in the Subpopulations and Intermediate Outcome Measures in COPD study cohort. Methods: Individuals were assigned to six predetermined exposure hazard categories based on self-reported employment history. Multivariable regression, adjusted for age, sex, race, current smoking status, and smoking pack-years determined the association of such exposures to odds of COPD and morbidity measures. We compared these with the results of a single summary question regarding occupational exposure. Results: A total of 2772 individuals were included. Some exposure estimates, including "gases and vapors" and "dust and fumes" exposures resulted in associations with effect estimates over two times the estimated effect size when compared with a single summary question. Conclusions: Use of occupational hazard categories can identify important associations with COPD morbidity while use of single-point measures may underestimate important differences in health risks. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Dust Morbidity Occupational Exposure Occupational Health Respiratory System Respiratory Tract Diseases Safety Solvents
• Keywords:
  Author Keywords: Occupational History Chronic Obstructive Pulmonary Disease Clinical Outcomes COPD Dusts Fumes Gases Morbidity Rates Observational Study Occupational Exposure Respiratory Disease Respiratory Diseases Vapors

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• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Alabama ; California ; Colorado ; Iowa ; Maryland ; Michigan ; New Hampshire ; New York ; North Carolina ; OSHA Region 1 ; OSHA Region 2 ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5 ; OSHA Region 7 ; OSHA Region 8 ; OSHA Region 9 ; Utah
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  65
• Issue:
  7
• NIOSHTIC Number:
  nn:20067952
• Citation:
  J Occup Environ Med 2023 Jul; 65(7):e443-e452
• Contact Point Address:
  Jennifer S. Rous, OSHA Region VIII, 1244 Speer Blvd, Ste 551, Denver, CO 80204
• Email:
  rous.jennifer@dol.gov
• Federal Fiscal Year:
  2023
• Performing Organization:
  Johns Hopkins University
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  20280630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:baba720e0350704039cb3a0b5814a410b1f10e3de5f8734b6c4121def1208b983a7a6ec40428d90ff66e414ed2963d804bcdb255c31ee66dabd0c7ee3aa199e2
• Download URL:
  https://stacks.cdc.gov/view/cdc/230184/cdc_230184_DS1.pdf
• File Type:
  [PDF - 624.70 KB ]