Details:

Alternative Title:
J Nat Prod
Publisher's site:
http://dx.doi.org/10.1021/np8003497
Personal Author:
Habib, Eman ; León, Francisco ; Bauer, John D. ; Hill, Robert A. ; Carvalho, Paulo ; ... More +
Habib, Eman ; León, Francisco ; Bauer, John D. ; Hill, Robert A. ; Carvalho, Paulo ; Cutler, Horace G. ; Cutler, Stephen J. Less -
Description:
A new compound, euparvic acid (1, C(14)H(16)O(6)), and the known compounds 5,7-dihydroxy-4-methylphthalide (2), 6-(3-carboxybutyl)-7-hydroxy-5-methoxy-4-methylphthalan-1-one (3), 6-(5-carboxy-3-methylpent-2-enyl)-7-hydroxy-5-methoxy-4-methylphthalan-1-one (4), and 6-(5-carboxy-4-hydroxy-3-methylpent-2-enyl)-7-hydroxy-5-methoxy-4-methylphthalan-1-one (5) were isolated from the EtOAc extract of Eupenicillium parvum. The structure of 1 was determined by interpretation of MS and homo- and heteronuclear 2D NMR spectroscopic data and confirmed by X-ray crystallography. The absolute configuration of 5 was determined via MPA ester derivatization.
Subject:
[+]
Anti-Bacterial Agents
Aspergillus Fumigatus
Candida Albicans
Cryptococcus Neoformans
Crystallography, X-Ray
Escherichia Coli
Eupenicillium
Methicillin-Resistant Staphylococcus Aureus
Microbial Sensitivity Tests
Molecular Conformation
Molecular Structure
Mycophenolic Acid
Note
Pseudomonas Aeruginosa

Source:
J Nat Prod. 2008; 71(11):1915-1918.
Document Type:
Journal Article
Funding:
5 U01 CI000211/CI/NCPDCID CDC HHS/United States ; C06 RR-14503-01/RR/NCRR NIH HHS/United States
5 U01 CI000211/CI/NCPDCID CDC HHS/United States ; C06 RR-14503-01/RR/NCRR NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:22f37bd7ecff435ba07bcb1059c329aadb9128a2491c991b58096cc9bbb0ffcd
File Type:

Supporting Files

• 	np-2008-003497_0004.jpg	jpeg
  	np8003497.nxml	txt
  	license.txt	txt
  	np-2008-003497_0001.gif	gif
  	np-2008-003497_0001.jpg	jpeg
  	np-2008-003497_0002.gif	gif
  	np-2008-003497_0002.jpg	jpeg
  	np-2008-003497_0003.gif	gif
  	np-2008-003497_0003.jpg	jpeg
  	np-2008-003497_0004.gif	gif

More +