CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.
As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
i
The effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts
-
Dec 28 2011
-
-
Source: BMC Pediatr. 2011; 11:121.
[PDF-237.03 KB]
Details:
-
Alternative Title:BMC Pediatr
-
Personal Author:
-
Description:Background
Cleft lip and/or palate (CL/P) increase mortality and morbidity risks for affected infants especially in less developed countries. This study aimed at assessing the effects of systematic pediatric care on neonatal mortality and hospitalizations of infants with cleft lip and/or palate (CL/P) in South America.
Methods
The intervention group included live-born infants with isolated or associated CL/P in 47 hospitals between 2003 and 2005. The control group included live-born infants with CL/P between 2001 and 2002 in the same hospitals. The intervention group received systematic pediatric care between the 7th and 28th day of life. The primary outcomes were mortality between the 7th and 28th day of life and hospitalization days in this period among survivors adjusted for relevant baseline covariates.
Results
There were no significant mortality differences between the intervention and control groups. However, surviving infants with associated CL/P in the intervention group had fewer hospitalization days by about six days compared to the associated control group.
Conclusions
Early systematic pediatric care may significantly reduce neonatal hospitalizations of infants with CL/P and additional birth defects in South America. Given the large healthcare and financial burden of CL/P on affected families and the relatively low cost of systematic pediatric care, improving access to such care may be a cost-effective public policy intervention.
Trial Registration
ClinicalTrials.gov: NCT00097149
-
Subjects:
-
Source:
-
Pubmed ID:22204448
-
Pubmed Central ID:PMC3277464
-
Document Type:
-
Funding:
-
Place as Subject:
-
Volume:11
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
