Ross, Macdonald, and a Theory for the Dynamics and Control of Mosquito-Transmitted Pathogens

Smith, David L.; Battle, Katherine E.; Hay, Simon I.; Barker, Christopher M.; Scott, Thomas W.; McKenzie, F. Ellis

doi:10.1371/journal.ppat.1002588

i

Ross, Macdonald, and a Theory for the Dynamics and Control of Mosquito-Transmitted Pathogens

Supporting Files

Apr 05 2012
By Smith, David L. ; Battle, Katherine E. ; Hay, Simon I. ; ...

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Alternative Title:

PLoS Pathog
Personal Author:

Smith, David L. ; Battle, Katherine E. ; Hay, Simon I. ; Barker, Christopher M. ; Scott, Thomas W. ; McKenzie, F. Ellis
Description:

Ronald Ross and George Macdonald are credited with developing a mathematical model of mosquito-borne pathogen transmission. A systematic historical review suggests that several mathematicians and scientists contributed to development of the Ross-Macdonald model over a period of 70 years. Ross developed two different mathematical models, Macdonald a third, and various "Ross-Macdonald" mathematical models exist. Ross-Macdonald models are best defined by a consensus set of assumptions. The mathematical model is just one part of a theory for the dynamics and control of mosquito-transmitted pathogens that also includes epidemiological and entomological concepts and metrics for measuring transmission. All the basic elements of the theory had fallen into place by the end of the Global Malaria Eradication Programme (GMEP, 1955-1969) with the concept of vectorial capacity, methods for measuring key components of transmission by mosquitoes, and a quantitative theory of vector control. The Ross-Macdonald theory has since played a central role in development of research on mosquito-borne pathogen transmission and the development of strategies for mosquito-borne disease prevention.
Subjects:

Animals Biology Communicable Disease Control Culicidae Disease Transmission, Infectious History, 20th Century Humans Malaria Models, Biological Review
Source:

PLoS Pathog. 2012; 8(4).
Pubmed ID:

22496640
Pubmed Central ID:

PMC3320609
Document Type:

Journal Article
Funding:

079091/Wellcome Trust/United Kingdom ; 095066/Wellcome Trust/United Kingdom ; 5 U01EH000418/EH/NCEH CDC HHS/United States ; U19AI089674/AI/NIAID NIH HHS/United States
Volume:

8
Issue:

4
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:6845079db48c774d95a146e9c042e59f0159bd4b4e28112110a25e94ef1a4d58
Download URL:

https://stacks.cdc.gov/view/cdc/22756/cdc_22756_DS1.pdf
File Type:

[PDF - 296.18 KB ]

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