Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Following the Largest Initial Epidemic Wave in the United States: Findings from New York City, 13 May to 21 July 2020

Details

• Personal Author:
  Cornell J ; Crawley A ; Daskalakis D ; Li J ; Maldin B ; Marovich S ; Pathela P ; Purdin J ; Schumacher PK ; Weiss D
• Description:
  Background: New York City (NYC) was the US epicenter of the spring 2020 coronavirus disease 2019 (COVID-19) pandemic. We present the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and correlates of seropositivity immediately after the first wave. Methods: From a serosurvey of adult NYC residents (13 May to 21 July 2020), we calculated the prevalence of SARS-CoV-2 antibodies stratified by participant demographics, symptom history, health status, and employment industry. We used multivariable regression models to assess associations between participant characteristics and seropositivity. Results: The seroprevalence among 45 367 participants was 23.6% (95% confidence interval, 23.2%-24.0%). High seroprevalence (>30%) was observed among black and Hispanic individuals, people from high poverty neighborhoods, and people in healthcare or essential worker industry sectors. COVID-19 symptom history was associated with seropositivity (adjusted relative risk, 2.76; 95% confidence interval, 2.65-2.88). Other risk factors included sex, age, race/ethnicity, residential area, employment sector, working outside the home, contact with a COVID-19 case, obesity, and increasing numbers of household members. Conclusions: Based on a large serosurvey in a single US jurisdiction, we estimate that just under one-quarter of NYC adults were infected in the first few months of the COVID-19 epidemic. Given disparities in infection risk, effective interventions for at-risk groups are needed during ongoing transmission. [Description provided by NIOSH]
• Subjects:
  Age Factors Aging Antibodies Communicable Diseases Demography Men Occupational Health Race Factors Safety Women Workplace

  More +
• Keywords:
  Age Factors Age Groups Author Keywords: SARS-CoV-2 COVID-19 Demographic Characteristics Employees Humans Models Obesity Racial Factors SARS-CoV-2 Seroepidemiology Seroprevalence Statistical Analysis Work Environment Workers

  More +
• ISSN:
  0022-1899
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  New York ; Ohio ; OSHA Region 2 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DFSE - Division of Field Studies and Engineering
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  196-206
• Volume:
  224
• Issue:
  2
• NIOSHTIC Number:
  nn:20063135
• Citation:
  J Infect Dis 2021 Jul; 224(2):196-206
• Contact Point Address:
  Preeti Pathela, DrPH, MPH, New York City Department of Health and Mental Hygiene, Gotham Center, 42-09 28th Street, Queens, New York 11101-4132
• Email:
  ppathela@health.nyc.gov
• Federal Fiscal Year:
  2021
• Peer Reviewed:
  True
• Source Full Name:
  The Journal of Infectious Diseases
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:122143b1bca517b73b18dfc43791eb9f4a2fbd8fe6b4b2948c68116300a9725bb76777bffc63c4e7baeef81f1c65a6d23f31e3b80373aeb02769b966afe6b940
• Download URL:
  https://stacks.cdc.gov/view/cdc/226253/cdc_226253_DS1.pdf
• File Type:
  [PDF - 350.55 KB ]