Predicting Future Asthma Morbidity in Preschool Inner-City Children

Details

• Personal Author:
  Breysse PN ; Curtin-Brosnan J ; Diette GB ; Hansel NN ; Matsui EC ; Mazique D ; McCormack MC ; Peng RD ; Rusher R
• Description:
  Background and aims: Children living in the inner city are particularly vulnerable to asthma. While we know much about factors that affect near-term outcomes in inner-city children, there is little evidence to guide clinicians on what to expect in the coming years, especially in preschool children. The purpose of our study was to determine which clinical and environmental factors are predictive of poor long-term asthma control in preschool inner-city children. Materials and methods: Baseline characteristics determined to be potential predictors of asthma severity were examined: demographics, asthma symptoms, medication use, healthcare utilization, early life medical history, family history, allergen exposure and allergic disease, and pollutant exposure. Bivariate and multivariate analyses were performed using logistic regression to examine the association of predictors of asthma severity with healthcare utilization at 2 years. Results: Of the 150 children at baseline, the follow-up rate was 83% at 2 years; therefore, 124 children were included in final analyses. At baseline, the mean age was 4.4 years and participants were predominantly African-American (90%). Most of the children were atopic and 32.5% reported using inhaled corticosteroids. Nighttime awakening from asthma and a history of pneumonia were predictive of future poor control. Conclusion: Preschool children with nighttime awakening from asthma and a history of pneumonia may deserve closer monitoring to prevent future asthma morbidity. [Description provided by NIOSH]
• Subjects:
  Asthma Asthma, Occupational Environmental Exposure Hypersensitivity Morbidity Occupational Health Race Factors Respiratory System Respiratory Tract Diseases Safety
• Keywords:
  Allergies Author Keywords: Asthma Children Environmental Exposure Health Care Inner City Morbidity Rates Preschool Children Racial Factors Respiratory Diseases
• ISSN:
  0277-0903
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  48
• Issue:
  8
• NIOSHTIC Number:
  nn:20062697
• Citation:
  J Asthma 2011 Oct; 48(8):797-803
• Contact Point Address:
  Nadia N. Hansel, M.D., M.PH., Johns Hopkins Asthma & Allergy Center, 5501 Hopkins Bayview Circle, Room 4B69, Baltimore, MD 21224, USA
• Email:
  nhansel1@jhmi.edu
• Federal Fiscal Year:
  2012
• Performing Organization:
  Johns Hopkins University
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Journal of Asthma
• End Date:
  20280630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2567065a59738a544462a1b5a1874f722ccd17d58a8299e35b6d20ae7bb90c3f63e5ea4e3deb7146b7161fd253a924e11130cce0faf927d922c05fff5f3c36af
• Download URL:
  https://stacks.cdc.gov/view/cdc/225893/cdc_225893_DS1.pdf
• File Type:
  [PDF - 341.25 KB ]