Arterial Stiffness Is Not Acutely Modified by Consumption of a Caffeinated Soft Drink Sweetened with High-Fructose Corn Syrup in Young Healthy Adults

Details

• Personal Author:
  Baker T ; Carter SJ ; Freemas JA ; Greenshields JT ; Johnson BD ; Schlader ZJ
• Description:
  We tested the hypothesis that ingestion of a caffeinated soft drink sweetened with high-fructose corn syrup acutely increases arterial stiffness. In a randomized counterbalanced, crossover design, fourteen healthy adults (25 +/- 3 years, 6 women) reported to the laboratory for two experimental visits where 500 ml of tap water (H2O) or 500 ml of Mountain Dew(R) (a caffeinated soft drink sweetened with high-fructose corn syrup (HFCS)) were consumed. Arterial stiffness (carotid-to-femoral pulse wave velocity (cfPWV)), peripheral and central blood pressures were measured pre-consumption, 30 min post-consumption, and 120 min post-consumption. Prior to each measurement period, beat-to-beat hemodynamic measures were collected. Changes in heart rate, blood pressure, and cardiac output from pre-consumption did not differ between trials at any timepoint (p >/= 0.06). Moreover, changes in peripheral or central blood pressures from pre-consumption did not differ between trials (p >/= 0.84). Likewise, changes in cfPWV from pre-consumption to 30 min post-consumption (HFCS: 0.2 +/- 0.3 m/s, H2O: 0.0 +/- 0.3 m/s, p = 0.34) and 120 min post-consumption (HFCS: 0.3 +/- 0.4 m/s, H2O: 0.2 +/- 0.3 m/s, p = 0.77) did not differ. Changes in aortic augmentation pressure, augmentation index, augmentation index corrected to a heart rate of 75 bpm, and reflection magnitude did not differ between conditions at 30 min post- (p >/= 0.55) or 120 min post- (p >/= 0.18) consumption. In healthy young adults, ingesting 500 ml of a commercially available caffeinated soft drink sweetened with high-fructose corn syrup does not acutely change indices of arterial stiffness and wave reflection. [Description provided by NIOSH]
• Subjects:
  Cardiovascular Diseases Cardiovascular System Men Occupational Health Safety Women
• Keywords:
  Author Keywords: Blood Pressure Blood Pressure Food Additives Heart Disease Heart Rate Hemodynamics High-fructose Corn Syrup Humans Pulse Wave Velocity Soft Drink
• ISSN:
  2051-817X
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Indiana ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  9
• Issue:
  7
• NIOSHTIC Number:
  nn:20062560
• Citation:
  Physiol Rep 2021 Apr; 9(7):e14777
• Contact Point Address:
  Zachary J. Schlader, H.H. Morris Human Performance Laboratories, Department of Kinesiology, School of Public Health, Indiana University, Bloomington, IN, USA
• Email:
  zschlade@indiana.edu
• Federal Fiscal Year:
  2021
• NORA Priority Area:
  Agriculture, Forestry and Fishing ; Construction
• Performing Organization:
  Indiana University, Bloomington
• Peer Reviewed:
  True
• Start Date:
  20190901
• Source Full Name:
  Physiological Reports
• End Date:
  20240831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d4f73f9a3bf71e6e7099ec84c37f4b34b5957fcceeefe831e5b65d28d27e348225dfab061e95ae8fea748923c36d42eb97812640f5bc058edbd4db787ffe6219
• Download URL:
  https://stacks.cdc.gov/view/cdc/225779/cdc_225779_DS1.pdf
• File Type:
  [PDF - 697.18 KB ]