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Examining Sleep Deficiency and Disturbance and Their Risk for Incident Dementia and All-Cause Mortality in Older Adults Across 5 Years in the United States



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  • Personal Author:
  • Description:
    Background: Sleep disturbance and deficiency are common among older adults and have been linked with dementia and all-cause mortality. Using nationally representative data, we examine the relationship between sleep disturbance and deficiency and their risk for incident dementia and all-cause mortality among older adults. Methods: The National Health and Aging Trends Study (NHATS) is a nationally-representative longitudinal study of Medicare beneficiaries in the US age 65 and older. Surveys that assessed sleep disturbance and duration were administered at baseline. We examined the relationship between sleep disturbance and deficiency and incident dementia and all-cause mortality over the following 5 years using Cox proportional hazards modeling, controlling for confounders. Results: Among the sample (n = 2,812), very short sleep duration (<=5 hours: HR = 2.04, 95% CI: 1.26 - 3.33) and sleep latency (>30 minutes: HR = 1.45, 95% CI: 1.03 - 2.03) were associated with incident dementia in adjusted Cox models. Difficulty maintaining alertness ("Some Days": HR = 1.49, 95% CI: 1.13 - 1.94 and "Most/Every Day": HR = 1.65, 95% CI: 1.17 - 2.32), napping ("Some days": HR = 1.38, 95% CI: 1.03 - 1.85; "Most/Every Day": HR = 1.73, 95% CI: 1.29 - 2.32), sleep quality ("Poor/Very Poor": HR = 1.75, 95% CI: 1.17 - 2.61), and very short sleep duration (<=5 hours: HR = 2.38, 95% CI: 1.44 - 3.92) were associated with all-cause mortality in adjusted Cox models. Conclusions: Addressing sleep disturbance and deficiency may have a positive impact on risk for incident dementia and all-cause mortality among older adults. [Description provided by NIOSH]
  • Subjects:
  • Keywords:
  • ISSN:
    1945-4589
  • Document Type:
    Text
  • Funding:
    Grant
  • Genre:
    Journal Article
  • Place as Subject:
  • CIO:
    National Institute for Occupational Safety and Health (NIOSH)
  • Topic:
    Workplace Safety & Health
  • Location:
    North America
  • Volume:
    13
  • Issue:
    3
  • NIOSHTIC Number:
    nn:20062449
  • Citation:
    Aging 2021 Feb; 13(3):3254-3268
  • Contact Point Address:
    Rebecca Robbins, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA
  • Email:
    rrobbins4@bwh.harvard.edu
  • Federal Fiscal Year:
    2021
  • NORA Priority Area:
    Healthcare and Social Assistance
  • Performing Organization:
    Brigham and Women's Hospital, Boston, Massachusetts
  • Peer Reviewed:
    True
  • Start Date:
    20190901
  • Source Full Name:
    Aging
  • End Date:
    20230831
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:bfbd55a386a2900f3f263ee8dc8a62c73ffef42eee49be349f496478310d21659f205a576051f8284adfb1d55b1341f12636a3fc24999ebbae4293ff7d87674e
  • Download URL:
  • File Type:
    Filetype[PDF - 782.80 KB ]
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