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i

Characterization and Evaluation of Performance of a Whole-Body Human Exposure Chamber



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  • Description:
    Objective: The purpose of this study is to characterize and evaluate the performance of a whole-body human exposure chamber for controlled test atmospheres of gases and particulates. Methods: The chamber is constructed from plexiglass with a volume of 75 ft2, operating at a flow rate of 55 cfm. Both the makeup and exhaust air are HEPA filtered. Fly ash dust is generated using a Wright Dust Feeder. An elutriator is used to eliminate particles larger than 10 microm. Direct-reading instrument Rupprecht and Patashnick PM-10 TEOM is used for determination of particle concentration. Particle size distributions are determined by a QCM cascade impactor. Gravimetric analysis is used to evaluate evenness of dust concentration in the chamber. CO2 is used as a tracer gas and its concentration was measured using Metrosonics aq-5000. Results: The dust concentration inside the chamber was found to be even with a variability of +/- 5.1%. Dust concentration, in microg/m3, at 0.2,0.4,0.6, and 1.6 RPMs were 110 +/- 3.8, 175 +/- 19, 387 +/- 26 and 538 +/- 17, respectively. For these RPMs, particle size distributions were associated with MMD 1.27 microm and GSD 2.35, MMD 1.39 and GSD 2.22, MMD 1.46 and GSD 2.08, MMD 1.15 and GSD 2.2. A good correlation between RPM setting and dust concentration was obtained with an R = 0.988. Concentrations of CO2 used for evaluation ranged from 6000 ppm to 18,000 ppm. Conclusions: The system produced predictable and consistent dust concentrations and particle size distributions. The various particle size distributions were not statistically different. The system can thus be reliably used for inhalation challenge procedures for both particulates and gases. [Description provided by NIOSH]
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  • CIO:
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  • Location:
  • Pages in Document:
    47
  • NIOSHTIC Number:
    nn:20062420
  • Citation:
    AIHce 2010: American Industrial Hygiene Conference and Exposition, May 22-27, 2010, Denver, Colorado. Falls Church, VA: American Industrial Hygiene Association, 2010 May; :47
  • Federal Fiscal Year:
    2010
  • Performing Organization:
    Sunshine Education and Research Center, University of South Florida
  • Peer Reviewed:
    False
  • Start Date:
    20050701
  • Source Full Name:
    AIHce 2010: American Industrial Hygiene Conference and Exposition, May 22-27, 2010, Denver, Colorado
  • End Date:
    20290630
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:1e03b8409a40af771dc1c5c8f754bddf89784c553309704e1895cd36691137c32295ffa76ab7bbdc23ad9815e7144991568d176741bf23cc8c0b4c1f8ffbc245
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  • File Type:
    Filetype[PDF - 1.26 MB ]
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