Lung Cancer Characteristics in the World Trade Center Environmental Health Center

Details

• Personal Author:
  Arslan AA ; Corona R ; Durmus N ; Henderson I ; Pehlivan S ; Reibman J ; Shao Y ; Sterman DH ; Zhang Y
• Description:
  The destruction of the World Trade Center (WTC) towers on 11 September 2001 resulted in acute and chronic dust and fume exposures to community members, including local workers and residents, with well-described aerodigestive adverse health effects. This study aimed to characterize lung cancer in the WTC Environmental Health Center (WTC EHC) focusing on gender and smoking history. WTC EHC patients undergo an initial evaluation that includes WTC exposure information, demographics, and tobacco use. Detailed cancer characteristics are recorded from pathology reports. As of 31 December 2019, 248 WTC EHC patients had a diagnosis of lung cancer. More patients with lung cancer were women (57%) compared to men (43%). Many cases (47% women, 51% men) reported acute dust cloud exposure. Thirty-seven percent of lung cancer cases with available smoking history were never-smokers (≤ 1 pack-years) and 42% had a ≤ 5 pack-year history. The median age of cancer diagnosis in never-smoking women was 61 years compared to 66 years in men. Adenocarcinoma was more common in never-smokers compared to ever-smokers (72% vs. 65%) and in women compared to men (70% vs. 65%). We provide an initial description of lung cancers in local community members with documented exposure to the WTC dust and fumes. [Description provided by NIOSH]
• Subjects:
  Lung Lung Diseases Neoplasms Occupational Health Respiratory System Respiratory Tract Diseases Safety September 11 Terrorist Attacks Sex Characteristics Smokers Tobacco Products

  More +
• Keywords:
  Author Keywords: September 11th Cancer Characteristics Cancer Rates Cigarette Smoking Lung Cancer Sex Factors Tobacco World Trade Center WTC WTC Environmental Health Center
• ISSN:
  1660-4601
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  18
• Issue:
  5
• NIOSHTIC Number:
  nn:20062403
• Citation:
  Int J Environ Res Public Health 2021 Mar; 18(5):2689
• Contact Point Address:
  Joan Reibman, Department of Medicine, Division of Pulmonary Medicine, School of Medicine (SOM), New York University, New York, NY 10016, USA
• Email:
  joan.reibman@nyulangone.org
• Federal Fiscal Year:
  2021
• Performing Organization:
  NYC Health + Hospitals (H+H): NYC H+H Data Center
• Peer Reviewed:
  True
• Start Date:
  20170401
• Source Full Name:
  International Journal of Environmental Research and Public Health
• End Date:
  20210331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b79f8ec9cef057aee938e3dc33097474c88181db0f43d60ee6fa55970b4c71d287738b7ebd3bcfc7940cef18a94f83b2697fba6ab85fd168fbff7950f44e5344
• Download URL:
  https://stacks.cdc.gov/view/cdc/225659/cdc_225659_DS1.pdf
• File Type:
  [PDF - 620.80 KB ]