Hormonal Reactivity to MRI Scanning in Adolescents

Details

• Personal Author:
  Eatough EM ; Hanson JL ; Pollak SD ; Shirtcliff EA
• Description:
  Magnetic resonance imaging (MRI) is a procedure that is now widely used to study emotional and cognitive processes in children and adolescents. However, the context within which brain imaging data are collected is a social context that may induce anxiety and stress.Several hormones have been shown to be responsive to environmental stressors. These stress responses may impact ability to successfully complete the procedure or collect imaging data. To investigate these issues, we measured salivary cortisol, dehydroepiandrosterone (DHEA), and testosterone in 160 adolescents during both a simulation (practice) and actual MRI. Hormones were all responsive to the MRI scan, indicating that an MRI scan itself can induce a stress response, with some hormones predicting the likelihood that an adolescent could successfully complete the scan with adequate data. The simulation scan did not hinder hormonal responses to the actual MRI. These data suggest that researchers should consider the effects of heightened hormonal reactivity to the scanning environment; adolescent's reactions to brain imaging may contribute to image data loss and may potentially influence outcome measures. [Description provided by NIOSH]
• Subjects:
  Adolescent Endocrine System Nervous System Occupational Health Safety
• Keywords:
  Adolescents Author Keywords: Stress Brain Electrical Activity Brain Function Children Cognitive Function Cortisol DHEA Environmental Stress Hormones Humans Magnetic Resonance Imaging MRI Reaction Rates Salivary Glands Simulation Scan Stress Testosterone

  More +
• ISSN:
  0306-4530
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Florida ; Louisiana ; OSHA Region 4 ; OSHA Region 5 ; OSHA Region 6 ; Wisconsin
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  34
• Issue:
  8
• NIOSHTIC Number:
  nn:20062309
• Citation:
  Psychoneuroendocrinology 2009 Sep; 34(8):1242-1246
• Contact Point Address:
  Erin M. Eatough, University of South Florida, Departmentof Psychology, 4202 E. Fowler Avenue, PCD 4118G, Tampa, FL 33620
• Email:
  eeatough@mail.usf.edu
• Federal Fiscal Year:
  2009
• Performing Organization:
  Sunshine Education and Research Center, University of South Florida
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Psychoneuroendocrinology
• End Date:
  20290630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2c52e74c46087f5db01e3e7a867e14bf24ad891687887eef4155ce6bea15f3777c13dddb379928f2493ac9aed7a34a528a3696c410f0c4c06f1eb2fde15d62e7
• Download URL:
  https://stacks.cdc.gov/view/cdc/225584/cdc_225584_DS1.pdf
• File Type:
  [PDF - 259.75 KB ]