External Societal Costs of Antimicrobial Resistance in Humans Attributable to Antimicrobial Use in Livestock

Details

• Personal Author:
  Davis MF ; Heaney CD ; Innes GK ; Korinek A ; Price LB ; Randad PR ; So AD
• Description:
  Antimicrobial use (AMU) in animal agriculture contributes to antimicrobial resistance (AMR) in humans, which imposes significant health and economic costs on society. Economists call these costs negative externalities, societal costs that are not properly reflected in market prices. We review the relevant literature and develop a model to quantify the external costs of AMU in animal agriculture on AMR in humans. Parameters required for this estimate include (a) the health and economic burden of AMR in humans,(b) the impact of AMU in animal agriculture on AMR in animals, (c) the fraction of AMR in humans attributable to animal agriculture, and (d) AMU in animals. We use a well-documented historic case to estimate an externality cost of about US$1,500 per kilogram of fluoroquinolones administered in US broiler chicken production. Enhanced data collection, particularly on the third and fourth parameters, is urgently needed to quantify more fully the externalities of AMU in animal agriculture [Description provided by NIOSH]
• Subjects:
  Agriculture Animal Husbandry Animals Economics Livestock Occupational Health Safety
• Keywords:
  Agricultural Industry AMR Animal Agriculture Animal Husbandry Antimicrobial Resistance Antimicrobials Author Keywords: Antimicrobial Resistance Costs Economic Impact Externality Human Health Livestock Industry Societal Cost

  More +
• ISSN:
  0163-7525
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  District of Columbia ; Maryland ; Massachusetts ; OSHA Region 1 ; OSHA Region 3 ; Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  141-157
• Volume:
  41
• NIOSHTIC Number:
  nn:20061825
• Citation:
  Annu Rev Public Health 2020 Apr; 41:141-157
• Contact Point Address:
  Christopher D. Heaney, Department of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
• Email:
  cheaney1@jhu.edu
• Federal Fiscal Year:
  2020
• Performing Organization:
  Johns Hopkins University
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Annual Review of Public Health
• End Date:
  20280630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a280185ff665b47a41955336e83d31cb76e3be660914b2b8e5a2db4fc9854132d6b4ecb7446c1c38d29f54c334f1edced287fa9246d5bef0571f165d12e3a4a4
• Download URL:
  https://stacks.cdc.gov/view/cdc/225198/cdc_225198_DS1.pdf
• File Type:
  [PDF - 324.72 KB ]