A Pilot Study: Characterizing Phthalate Exposure Among Nail Salon Workers

Details

• Personal Author:
  Calafat A ; Duty S ; Hauser RB
• Description:
  Background: Dibutyl phthalate (DBP) is used to reduce brittleness and cracking in nailpolish. DBP is a reproductive toxicant in rodents, and in humans it has been associated with allergic reactions as well as reproductive and respiratory impairments. To determine if manicurists are occupationally exposed to DBP, a pilot study is underway. Methods: Between January 2004 and October 2004, 19 female and 2 male manicurists were recruited. Five manicurists worked in shops with local exhaust ventilation while the others did not. Urine samples were collected before and after work on the same day. Phthalate monoester concentrations were measured by automated solid phase extraction coupled with isotope-dilution-high performance liquid chromatography-tandem mass spectrometry. Results: Monobutyl phthalate (MBP) was detected in all manicurists. Median MBP levels among the women and men were more than 2 and 5 times higher, respectively, than general population levels. MBP levels increased 6.9 ng/mL across the work shift. MBP levels rose 12.9 ng/mL across the work shift in shops without local exhaust ventilation, compared to a decrease of 0.74 ng/mL in shops with local exhaust ventilation. None of the above findings reached statistical significance. Conclusion: This pilot study quantified occupational exposure of manicurists to DBP. Although the sample size is small, observed suggestive associations indicate manicurists are being exposed to DBP during work and that local exhaust ventilation can mitigate that exposure. These analyses will need to be repeated once recruitment is completed to confirm the robustness of the findings. [Description provided by NIOSH]
• Subjects:
  Men Occupational Health Phthalic Acids Respiratory Tract Diseases Safety Urine Urogenital System Ventilation Women Workplace
• Keywords:
  Dibutyl Phthalate Exhaust Ventilation Humans Liquid Chromatography Mass Spectrometry Nail Technicians Phthalates Reproductive Effects Respiratory System Disorders Urinalysis Work Environment Workers

  More +
• Publisher:
  American Public Health Association
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:20061397
• Citation:
  APHA 133rd Annual Meeting and Exposition, Philadelphia, Pennsylvania, December 10-14, 2005. Washington, DC: American Public Health Association, 2005 Dec; :114231
• Contact Point Address:
  Susan Duty, MSN, ScD, Department of Nursing, Simmons College, 300 The Fenway, Science Building room 314, Boston, MA 02115
• Email:
  susan.duty@simmons.edu
• CAS Registry Number:
  Dibutyl phthalate (CAS RN 84-74-2) ; Monobutyl phthalate (CAS RN 131-70-4)
• Federal Fiscal Year:
  2006
• Performing Organization:
  Harvard School of Public Health
• Peer Reviewed:
  False
• Start Date:
  20050701
• Source Full Name:
  APHA 133rd Annual Meeting and Exposition, Philadelphia, Pennsylvania, December 10-14, 2005
• End Date:
  20280630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6ee31246b9ba88ce3f43497995e252d4550af50621581a2747bdc5d24f293a9d54a4ad85644da3fa0274017745871067b21d1c44d246c95510588f9c6f8f81fd
• Download URL:
  https://stacks.cdc.gov/view/cdc/224935/cdc_224935_DS1.pdf
• File Type:
  [PDF - 74.23 KB ]