Night Shift Work Surrounding Pregnancy and Offspring Risk of Atopic Disease

Details

• Personal Author:
  Drucker AM ; Eliassen AH ; Rada S ; Schernhammer ES ; Strohmaier S
• Description:
  Background: Night shift work surrounding pregnancy may contribute to the risk of developing atopic diseases in offspring due to alterations in the prenatal environment, from stress. Objective: To examine the association of maternal night shift work surrounding pregnancy and offspring risk of developing atopic diseases from childhood to adolescence. Methods: We examined the association between night shift work before and during pregnancy among 4,044 mothers in the Nurses' Health Study II (NHSII) and atopic dermatitis, asthma and hay fever risk in 4,813 of their offspring enrolled in the Growing Up Today Study (GUTS). Mothers reported whether GUTS participants had ever been diagnosed with atopic dermatitis, asthma or hay fever in the GUTS Mothers' questionnaire. Generalized estimating equation regression models were used to estimate multivariable adjusted odds ratios (OR) and 95% confidence intervals (CIs). Results: There were no significant associations between pre-conception maternal night shift work and risk of atopic dermatitis, asthma or hay fever in their offspring. Among 545 mothers with information on night shift work during pregnancy, shift work also was not associated with atopic dermatitis, asthma or hay fever in the offspring. Stratified analyses by history of parental atopy and maternal chronotype showed some statistically significant findings, but they were inconsistent and no significant interaction was seen with increasing duration of night shift work. Conclusion: In this study, night shift work before and during pregnancy did not increase offspring risk of developing atopic dermatitis, asthma or hay fever. [Description provided by NIOSH]
• Subjects:
  Adolescent Asthma Asthma, Occupational Dermatitis Environmental Exposure Epidemiology Occupational Health Pregnancy Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety Shift Work Schedule Skin Surveys And Questionnaires Women

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• Keywords:
  Adolescents Bronchial Asthma Children Dermal Exposures Etiology Exposure Levels Health Effects Humans Models Prenatal Exposure Questionnaires Risk Factors Shift Work Shift Workers Statistical Analysis Stress

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• ISSN:
  1932-6203
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  15
• Issue:
  4
• NIOSHTIC Number:
  nn:20060547
• Citation:
  PLoS One 2020 Apr; 15(4):e0231784
• Contact Point Address:
  Eva S. Schernhammer, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts
• Email:
  eva.schernhammer@meduniwien.ac.at
• Federal Fiscal Year:
  2020
• Performing Organization:
  Brigham and Women's Hospital, Inc., Boston, Massachusetts
• Peer Reviewed:
  True
• Start Date:
  20100801
• Source Full Name:
  PLoS One
• End Date:
  20190831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:ccf0f7207850f73a0a8e91e6e5cacbf78a3f2af29cbb9b918f23b7be9bea352c7c752dd233c658aeabde37a90a17d8d204ddf9ee92142817e92c255470600d38
• Download URL:
  https://stacks.cdc.gov/view/cdc/224414/cdc_224414_DS1.pdf
• File Type:
  [PDF - 534.16 KB ]