Dose Prediction Modeling for Epidemiologic Assessment of Pesticide Exposure Risks in Occupational Cohorts

Details

• Personal Author:
  Harris SA ; Wells KM
• Description:
  Epidemiologic studies designed to evaluate the effects of commonly used turf pesticides may have limited power to detect health risks and may be subject to bias from exposure measurement error. To increase the accuracy and precision of dose estimation for both risk assessment and epidemiologic research, valid models must be developed. Further, repeated measures of exposures over time are necessary to estimate both inter- and intra-individual variation. To address some of these issues, a national study of TruGreen Chemlawn employees was initiated in 2003. In the pilot study, conducted in Richmond, Virginia, up to 19 days of 24-hour urine samples were collected from 22 individuals. In 2004, urine samples were collected from a total of 113 volunteers in the spring, summer and fall, from 5 locations across the United States. The design of this study, the selection of national locations and pesticides, urine sampling methodology, and statistical modeling efforts are described. [Description provided by NIOSH]
• Subjects:
  Epidemiology Insecticides Occupational Exposure Occupational Health Safety
• Keywords:
  Biological Monitoring Dose Reconstruction Exposure Assessment Occupational Exposure Pesticides And Agricultural Chemicals Risk Assessment
• ISBN:
  9780841239746
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Book
• Place as Subject:
  OSHA Region 3 ; Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  187-200
• Volume:
  951
• NIOSHTIC Number:
  nn:20060270
• Citation:
  Assessing exposures and reducing risks to people from the use of pesticides. ACS Symposium Series. Krieger RI, Ragsdale N, Seiber JN eds. Washington, D.C.: American Chemical Society, 2007 Feb; 951:187-200
• Contact Point Address:
  Shelley A. Harris, Department of Epidemiology and Community Health, P.O. Box 843050, Virginia Commonwealth University, Richmond, VA 23284-3050
• Email:
  saharris@vcu.edu
• Editor(s):
  Krieger RI; Ragsdale N; Seiber JN
• Federal Fiscal Year:
  2007
• Performing Organization:
  Virginia Commonwealth University, Richmond, Virginia
• Peer Reviewed:
  True
• Start Date:
  20020801
• Source Full Name:
  Assessing exposures and reducing risks to people from the use of pesticides
• End Date:
  20050731
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b22864582aeb6da6eceb849ab49fc1e4fc8bcfda97c30d3b15b5cebcd3c399ecebb054e615f97fd51b74399342b90e4c366ec77a4cde5896bb63ede9cdcf22ee
• Download URL:
  https://stacks.cdc.gov/view/cdc/224225/cdc_224225_DS1.pdf
• File Type:
  [PDF - 279.37 KB ]