Pulmonary Response to Ozone Exposures in Healthy Individuals Aged 55 Years or Greater

Details

• Personal Author:
  Koenig JQ ; Kusic G ; McManus MS ; Pierson WE ; Reisenauer CS ; Smith MS
• Description:
  Since minimal data are available regarding the pulmonary effects of ozone (O3) in healthy individuals over the age of 55, this research was designed to determine if this group was at risk for pulmonary function changes when exposed to O3 at ambient concentrations for one hour during intermittent exercise. Ten female and nine male subjects were exposed for 60 minutes in random order to one of the following O3 concentrations: 0.0, 0.2, or 0.3 ppm. All exposures were administered through a rubber mouthpiece while the subject was either at rest or moderately exercising on a treadmill. The following pulmonary function tests (PFT) were recorded before exposure, and at periods immediately following and 20 minutes postexposure: total respiratory resistance (RT), thoracic gas volume at functional residual capacity (FRC), and forced expiratory volume in one second (FEV1). Baseline PFT mean values and air exposure PFT mean values were compared through the use of repeated measure two-way analysis of variance to detect any significant effect of exposure on these parameters. Following 60 minutes of exposure at light intermittent exercise, there were no statistically significant pulmonary functional changes observed in male subjects. However, in female subjects, a statistically significant increase in RT was observed. [Description provided by NIOSH]
• Subjects:
  Aging Lung Occupational Health Ozone Respiratory System Safety Sex Characteristics
• Keywords:
  Age Groups Exposure Assessment Gender Factors Pulmonary Effects Pulmonary Function
• ISSN:
  0002-2470
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 10 ; OSHA Region 9 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  51-55
• Volume:
  38
• Issue:
  1
• NIOSHTIC Number:
  nn:20060157
• Citation:
  J Air Pollut Control Assoc 1988 Jan; 38(1):51-55
• CAS Registry Number:
  Ozone (CAS RN 10028-15-6)
• Federal Fiscal Year:
  1988
• Performing Organization:
  University of Washington, Seattle, Washington
• Peer Reviewed:
  True
• Start Date:
  19770930
• Source Full Name:
  Journal of the Air Pollution Control Association
• End Date:
  19920630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:9d0cea6081d47539333158a41b1483c6ab5a823cdc5dd71aa12f1ccc40ec41bb334c5513d8052daff2018cd7b75c8f8b9e363d70947c99fa2d54c7ff70a7e9aa
• Download URL:
  https://stacks.cdc.gov/view/cdc/224156/cdc_224156_DS1.pdf
• File Type:
  [PDF - 456.11 KB ]