Dysplastic Nevi: Markers for Increased Risk for Melanoma

Details

• Personal Author:
  Friedman RJ ; Heilman ER ; Kopf AW ; Levenstein M ; Rigel DS ; Rivers JK ; Vinokur AF
• Description:
  A total of 452 white patients, classified into four dysplastic nevi groups, were followed prospectively by repetitive, complete cutaneous examinations using total-body photographs taken on entry into the study. Sixteen patients (3.5%) developed 18 newly diagnosed malignant melanomas (MM) during an average follow-up period of 27 months. Twelve of the 18 MM were in situ, and all of the six primary invasive MM diagnosed prospectively in this follow-up were less than 0.89 mm in Breslow thickness, implying an excellent prognosis. Compared with reference populations, the number of MM detected significantly exceeded the number estimated to occur in the comparable age-matched control groups. These data support the concept of repetitive follow-ups of all groups of patients with dysplastic nevi. [Description provided by NIOSH]
• Subjects:
  Neoplasms Occupational Health Pathology Safety Skin Skin Diseases
• Keywords:
  Biological Monitoring Cancer Medical Examinations Skin Cancer
• ISSN:
  0008-543X
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  386-389
• Volume:
  63
• Issue:
  2
• NIOSHTIC Number:
  nn:20060049
• Citation:
  Cancer 1989 Jan; 63(2):386-389
• Contact Point Address:
  Darrell S. Rigel, MD, Oncology Section, Skin and Cancer Unit, 562 First Avenue, New York, NY 10016
• Federal Fiscal Year:
  1989
• Performing Organization:
  New York University, New York, New York
• Peer Reviewed:
  True
• Start Date:
  19790401
• Source Full Name:
  Cancer
• End Date:
  19820331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:1825d4b0d70ab8d08ba9066f4afb9f7ec799ed3f7d155932a26a8ba187af406a2ce36462b527997cf07227fb60ec5e5dc1042651cc8bb5be486def1149056efb
• Download URL:
  https://stacks.cdc.gov/view/cdc/224082/cdc_224082_DS1.pdf
• File Type:
  [PDF - 361.71 KB ]