Clinical Characteristics of Malignant Melanomas Developing in Persons with Dysplastic Nevi

Details

• Personal Author:
  Friedman RJ ; Heilman ER ; Kopf AW ; Levenstein M ; Rigel DS ; Rivers JK ; Vinokur AF
• Description:
  A total of 452 patients with dysplastic nevi (DN) were followed prospectively by repetitive, complete cutaneous examinations in order to determine the clinical features of early malignant melanomas (MM) arising in them. Sixteen patients (3.5%) developed 18 newly diagnosed MM during an average follow-up period of 27 months. Twelve of the 18 MM were in situ and all of the primary invasive MM diagnosed prospectively in this follow-up were less than 0.89 mm in Breslow thickness, implying an excellent prognosis. The principal clinical clue to the diagnosis of MM was change in a preexisting pigmented lesion. Total-body photographs were very useful in helping to identify the early MM in these patients. [Description provided by NIOSH]
• Subjects:
  Diagnosis Neoplasms Occupational Health Pathology Safety Skin Skin Diseases
• Keywords:
  Cancer Clinical Diagnosis Medical Examinations Skin Cancer
• ISSN:
  0008-543X
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  65
• Issue:
  5
• NIOSHTIC Number:
  nn:20056738
• Citation:
  Cancer 1990 Mar; 65(5):1232-1236
• Contact Point Address:
  Alfred W. Kopf, MD, Oncology Section, Skin and Cancer Unit, 562 First Avenue, New York, NY 10016
• Federal Fiscal Year:
  1990
• Performing Organization:
  New York University, New York, New York
• Peer Reviewed:
  True
• Start Date:
  19790401
• Source Full Name:
  Cancer
• End Date:
  19820331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:e96e3a289e93dfe8018a41c3bbe27701c951dd57b1277cc3448bb6c54178053fccc338ace5eee376dc5b1598f1bb647327e10ab6fd1349c9100a5c634743e1cf
• Download URL:
  https://stacks.cdc.gov/view/cdc/214288/cdc_214288_DS1.pdf
• File Type:
  [PDF - 470.73 KB ]