Riveting Hammer Vibration Damages Mechanosensory Nerve Endings

Details

• Personal Author:
  Bain JLW ; Grétarsson SL ; Lindell H ; Riley, Danny A. ; Wu C ; Zimmerman JJ
• Description:
  Hand-arm vibration syndrome (HAVS) is an irreversible neurodegenerative, vasospastic, and musculoskeletal occupational disease of workers who use powered hand tools. The etiology is poorly understood. Neurological symptoms include numbness, tingling, and pain. This study examines impact hammer vibration-induced injury and recoverability of hair mechanosensory innervation. Rat tails were vibrated 12 min/d for 5 weeks followed by 5 week recovery with synchronous non-vibrated controls. Nerve fibers were PGP9.5 immunostained. Lanceolate complex innervation was compared quantitatively in vibrated vs sham. Vibration peak acceleration magnitudes were characterized by frequency power spectral analysis. Average magnitude (2515 m/s2, root mean squared) in kHz frequencies was 109 times that (23 m/s2) in low Hz. Percentage of hairs innervated by lanceolate complexes was 69.1% in 5-week sham and 53.4% in 5-week vibration generating a denervation difference of 15.7% higher in vibration. Hair innervation was 76.9% in 5-weeks recovery sham and 62.0% in 5-week recovery vibration producing a denervation difference 14.9% higher in recovery vibration. Lanceolate number per complex (18.4 +/- 0.2) after vibration remained near sham (19.3 +/- 0.3), but 44.9% of lanceolate complexes were abnormal in 5 weeks vibrated compared to 18.8% in sham. The largest vibration energies are peak kHz accelerations (approximately 100000 m/s2) from shock waves. The existing ISO 5349-1 standard excludes kHz vibrations, seriously underestimating vibration injury risk. The present study validates the rat tail, impact hammer vibration as a model for investigating irreversible nerve damage. Persistence of higher denervation difference after 5-week recovery suggests repeated vibration injury destroys the capability of lanceolate nerve endings to regenerate. [Description provided by NIOSH]
• Subjects:
  Environmental Exposure Laboratories Nervous System Nervous System Diseases Occupational Health Risk Assessment Risk Factors Safety Vibration
• Keywords:
  Acceleration Author Keywords: Denervation Exposure Assessment Exposure Levels Hand-arm Vibration Syndrome Hand Tools HAVS Laboratory Animals Laboratory Testing Mechanosensory Nerve Damage Nerve Fiber Excitation Nerve Fibers Nerves Neurodegeneration Neurological Disorders Neurological Reactions Peripheral Nervous System PGP9.5 Power Tools Risk Factors Shock Wave Shock Waves Standards Vibration Disease Vibration Effects Vibration Exposure

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• ISSN:
  1085-9489
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 5 ; OSHA Region 6 ; Texas ; Wisconsin
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  279-287
• Volume:
  25
• Issue:
  3
• NIOSHTIC Number:
  nn:20059932
• Citation:
  J Peripher Nerv Syst 2020 Sep; 25(3):279-287
• Contact Point Address:
  Danny A. Riley, PhD, 13701 Evergreen Way, Austin, TX 78737
• Email:
  darileyshuttle@gmail.com
• Federal Fiscal Year:
  2020
• Performing Organization:
  Medical College of Wisconsin, Milwaukee, Wisconsin
• Peer Reviewed:
  True
• Start Date:
  20110901
• Source Full Name:
  Journal of the Peripheral Nervous System
• End Date:
  20160831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b1fbe82befc914005049b30656a3d7e2779f5ea45bfdefccdd309905f011d17d22bc2a5e05a703c23dbcec4ffa222c18b1207cd67ad517ca20a67958731a229d
• Download URL:
  https://stacks.cdc.gov/view/cdc/223985/cdc_223985_DS1.pdf
• File Type:
  [PDF - 683.94 KB ]