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A Model for Patient-Direct Screening and Referral for Familial Cancer Risk



Details

  • Personal Author:
  • Description:
    Patients at increased familial risk of cancer are sub-optimally identified and referred for genetic counseling. We describe a systematic model for information collection, screening and referral for hereditary cancer risk. Individuals from three different clinical and research populations were screened for hereditary cancer risk using a two-tier process: a 7-item screener followed by review of family history by a genetic counselor and application of published criteria. A total of 869 subjects participated in the study; 769 in this high risk population had increased familial cancer risk based on the screening questionnaire. Of these eligible participants, 500 (65.0 %) provided family histories and 332 (66.4 %) of these were found to be at high risk of a hereditary cancer syndrome, 102 (20.4 %) at moderate familial cancer risk, and 66 (13.2 %) at average risk. Three months following receipt of the risk result letter, nearly all respondents found the process at least somewhat helpful (98.4 %). All participants identified as high-risk were mailed a letter recommending genetic counseling and were provided appointment tools. After 1 year, only 13 (7.3 %) of 179 high risk respondents reported pursuit of recommended genetic counseling. Participants were willing to provide family history information for the purposes of risk assessment; however, few patients pursued recommended genetic services. This suggests that cancer family history registries are feasible and viable but that further research is needed to increase the uptake of genetic counseling. [Description provided by NIOSH]
  • Subjects:
  • Keywords:
  • ISSN:
    1389-9600
  • Document Type:
    Text
  • Funding:
    Grant
  • Genre:
    Journal Article
  • Place as Subject:
  • CIO:
    National Institute for Occupational Safety and Health (NIOSH)
  • Topic:
    Workplace Safety & Health
  • Location:
    North America
  • Volume:
    15
  • Issue:
    4
  • NIOSHTIC Number:
    nn:20064560
  • Citation:
    Fam Cancer 2016 Oct; 15(4):707-716
  • Contact Point Address:
    Kristin B Niendorf, Masonic Cancer Center, University of Minnesota, 420 Delaware Street SE, MMC 450, Minneapolis, MN, 55455, USA
  • Email:
    baker603@umn.edu
  • Federal Fiscal Year:
    2017
  • Performing Organization:
    University of Minnesota Twin Cities
  • Peer Reviewed:
    True
  • Start Date:
    20050701
  • Source Full Name:
    Familial Cancer
  • End Date:
    20250630
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:ab9938e758fc91f54ab1f35a5c7adb6665d7436054a1f7bf6836c2c1b7bc34f0ebf7ee09923eef380d3603b080f14f3633dcff37b5c888fcb29f6ee2e80883ef
  • Download URL:
  • File Type:
    Filetype[PDF - 668.78 KB ]
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