High-Fat Western Diet Consumption Exacerbates Silica-Induced Pulmonary Inflammation and Fibrosis (Dataset)

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  Download the Dataset decsribed here from Data.cdc.gov at https://doi.org/10.26616/NIOSHRD-1032-2022-0. ; Adipose tissue (AT), an endocrine organ, plays a central role in maintenance of whole-body energy homeostasis through its release of adipokines. Obesity, affecting over 40% of American adults, disrupts adipocyte metabolism leading to chronic systemic inflammation and metabolic dysfunction (MetDys). MetDys is associated with impaired lung function, pulmonary hypertension, and asthma. The aim of this study was to investigate the effects of high-fat Western diet (HFWD)-consumption on silica-induced pulmonary inflammation and fibrosis in the F344 rat. Description provided by NIOSH
• Subjects:
  • Animals
  • Body Weight
  • Diet
  • Lung
  • Lung Diseases
  • Occupational Health
  • Respiratory System
  • Respiratory Tract Diseases
  • Safety
  • Silicon Dioxide
• Keywords:
  • Adipose tissue
  • Obesity
  • Body weight
  • Metabolic disorders
  • Lung function
  • Pulmonary system
  • Lung fibrosis
  • Silica
  • Dietary effects
  • Diet
  More +
• Series:
  NIOSH Data
• DOI:
  https://doi.org/10.26616/NIOSHRD-1032-2022-0
• Landing Page:
  https://stacks.cdc.gov/view/cdc/222970
• Dataset Download URL:
  https://data.cdc.gov/download/eur4-ng38/application%2Fx-zip-compressed
• Identifier:
  https://doi.org/10.26616/NIOSHRD-1032-2022-0
• Format:
  ZIP folder
• Document Type:
  Dataset
• Genre:
  Research Dataset
• Place as Subject:
  OSHA Region 3 ; West Virginia
• Media Type:
  application/zip
• Described By Type:
  HTML Repository Page
• License:
  https://creativecommons.org/public-domain/
• Rights:
  Public Domain
• Described By:
  https://stacks.cdc.gov/view/cdc/222970
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Contact Point:
  Health Effects Laboratory Division (HELD). Pathology and Physiology Research Branch (PPRB)
• Pages in Document:
  1 ZIP folder
• NIOSHTIC Number:
  nn:20064523
• Citation:
  Morgantown, WV: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Research Dataset RD-1032-2022-0, 2022 May; :dataset
• Email:
  sa-cin-webteam@cdc.gov
• CAS Registry Number:
  • Quartz (SiO2) (CAS RN 14808-60-7)
• Federal Fiscal Year:
  2022
• NORA Priority Area:
  Construction ; Mining
• Peer Reviewed:
  False
• Download URL:
  https://stacks.cdc.gov/view/cdc/222970/cdc_222970_DS1.pdf
• File Type:
  [PDF - 755.31 KB]
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:54ce4c9c4dedc56773e39664082ace8b93a438d9e6444d790378de7eb5d59d9572bb3d582a4419b86744b71a4d117445c6d04b97ee6b2a6ea98c5eee686a1d7f